Cell cycle events are coordinated by cyclin-dependent kinases (CDKs) to ensure robust cell division. CDK4/6 and CDK2 regulate the growth 1 (G1) to synthesis (S) phase transition of the cell cycle...
Certain people occupy topological positions within social networks that enhance their effectiveness at inducing spillovers. We mapped face-to-face networks among 24,702 people in 176 isolated vil...
The developmental decision made by malaria parasites to become sexual underlies all malaria transmission. Here, we describe a rich atlas of short- and long-read single-cell transcriptomes of over...
B lymphocytes are essential mediators of humoral immunity and play multiple roles in human cancer. To decode the functions of tumor-infiltrating B cells, we generated a B cell blueprint encompass...
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Semiconductor hydrogels enable active bioelectronics
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Marine stratocumulus clouds are the “global reflectors,” sharply contrasting with the underlying dark ocean surface and exerting a net cooling on Earth’s climate. The magnitude of this cool...
Natural infections are distinct from those of laboratory—or zombie—strains
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Two types of B cell in the tumor microenvironment modulate antitumor immunity
Global biodiversity decline is a pressing environmental challenge in the 21st century (1), and both international platforms, such as the United Nations Conference of the Parties (2), and regional...
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Pakistan is home to two otter species, the Eurasian otter (Lutra lutra) and the smooth-coated otter (Lutrogale perspicillata). Two decades ago, these species thrived in habitats across Pakistan, ...
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Department of Energy funds research to take carbon out of iron and steel production
Thomas Südhof says mistakes in co-authored publications are honest errors that don’t affect studies' conclusions
Hardy zircon minerals found in Australian rocks suggest conditions for life existed 4 billion years ago
https://www.science.org/content/article/ancient-crystals-suggest-early-earth-had-land-and-freshwater
Drop in 21st Century Cures Act funding will slow BRAIN and All of Us projects
At the end of May, 194 member states of the World Health Organization (WHO) will meet for the World Health Assembly. Negotiations underway now will determine whether they vote then to adopt a pan...
Next round of international climate simulations will seek to curb excess energy use for computation
https://www.science.org/content/article/climate-modelers-grapple-their-own-carbon-emissions
Short telomeres cause age-related disease, and long telomeres contribute to cancer; however, the mechanisms regulating telomere length are unclear. We developed a nanopore-based method, which we ...