Researchers used vascular smooth muscle-specific leucine-rich repeat-containing family 8 A (LRRC8A) knockout mice and an angiotensin II-induced hypertension model.
The authors revealed a direct differentiation pathway from HSCs into platelets that is progressively propagated upon aging. The aging-enriched platelet path was decoupled from all other hematopo...
Scientists demonstrated that autophagy was an adaptive cytoprotective response to chronic inflammation in the aging murine bone marrow niche.
Scientists evaluated carbon monoxide (CO)-induced autophagy in human(h) MSCs, and its impact on cell function in murine cecal ligation and puncture.
Researchers described the functions of linc-adipose anti-inflammatory (ADAIN), an adipose lincRNA that was downregulated in white adipose tissue of obese humans.
Investigators showed that microRNA activity, which was otherwise dispensable for preimplantation development, was essential for the adaptation of early mouse embryos to the dormant state of diap...
Researchers used hPSCs which formed compact colonies consisting of dynamically active cells at the periphery and epithelial-like cells at the core.
The authors collated a list of 1141 genes in connection to the term “endocytosis” from Kyoto Encyclopedia of Genes and Genomes and Gene Ontology and examined the effect of their knockdown on...
Investigators performed prospective lineage tracing of human embryos using live imaging, non-invasive cell labeling, and computational predictions to determine the contribution of each 2-cell st...
Scientists describe the similarities and differences of the expression pattern in space and in time of mammalian Hes/zebrafish Her genes and their targets in different tissues.
The Maryland Stem Cell Research Commission announced the next round of awards granting a total of more than $15.4 million. These awards are aimed at fostering groundbreaking research to enhance ...