Implementation of clinical metagenomics and pathogen genomic surveillance can be particularly challenging due to the lack of bioinformatics tools and/or expertise. In order to face this challenge...
https://genomemedicine.biomedcentral.com/articles/10.1186/s13073-024-01334-3
The "missing" heritability of complex traits may be partly explained by genetic variants interacting with other genes or environments that are difficult to specify, observe, and detect. We propos...
https://genomemedicine.biomedcentral.com/articles/10.1186/s13073-024-01329-0
Pituitary neuroendocrine tumors (PitNETs) are common gland neoplasms demonstrating distinctive transcription factors. Although the role of immune cells in PitNETs has been widely recognized, the ...
https://genomemedicine.biomedcentral.com/articles/10.1186/s13073-024-01325-4
Gut dysbiosis has been linked with both HIV infection and diabetes, but its interplay with metabolic and inflammatory responses in diabetes, particularly in the context of HIV infection, remains ...
https://genomemedicine.biomedcentral.com/articles/10.1186/s13073-024-01336-1
Klebsiella pneumoniae is a major bacterial and opportunistic human pathogen, increasingly recognized as a healthcare burden globally. The convergence of resistance and virulence in K. pneumoniae ...
https://genomemedicine.biomedcentral.com/articles/10.1186/s13073-024-01332-5