In reply to Vitaly. You'd be expected to work till the very death (...) And making savings likely won't be ...
https://lemire.me/blog/2015/06/09/aging-software-bug/#comment-291195
I know this is an old post, but I wonder how this would affect younger generation and inequality? If people would stay in perfect physical and mental shape up until the old age, wouldn't that giv...
https://lemire.me/blog/2015/06/09/aging-software-bug/#comment-291193
@Andersen and @de Grey Thanks for these excellent answers.
https://lemire.me/blog/2015/06/09/aging-software-bug/#comment-169005
Thanks. We're making good progress here, though I do rather wish you would get out of the habit of writing in a tone that implies you are sure I won't have good answers to your objections. "Hormo...
https://lemire.me/blog/2015/06/09/aging-software-bug/#comment-168998
I do not see the hormone issue as in any way insurmountable because current progress in technology will address these and other issues such as Thymus rejuvenation which is something SENS is alrea...
https://lemire.me/blog/2015/06/09/aging-software-bug/#comment-168995
@de Grey Let me illustrate what I have in mind. Hormone levels are all out of range as you grow old. How do you fix that? I guess that the thought is that the seven repair pathways of SENS will g...
https://lemire.me/blog/2015/06/09/aging-software-bug/#comment-168960
Lots to clarify here. "I do not think we believe that nuclear DNA is affected very much with age." My position on this is outlined in PubMed 17588643; in brief, we certainly do need to worry abou...
https://lemire.me/blog/2015/06/09/aging-software-bug/#comment-168909
@John Andersen it's accumulation of intra and extracellular aggregates and mutations in the nuclear and mitochondrial DNA that lead to the increased risk of pathology I do not think we b...
https://lemire.me/blog/2015/06/09/aging-software-bug/#comment-168877
John - yes, one's natural image of wear and tear at the macroscopic level is not a particularly faithful description of the damage of aging. However, I don't feel too bad about using the term (or...
https://lemire.me/blog/2015/06/09/aging-software-bug/#comment-168583
its not wear and tear it's accumulation of intra and extracellular aggregates and mutations in the nuclear and mitochondrial DNA that lead to the increased risk of pathology.
https://lemire.me/blog/2015/06/09/aging-software-bug/#comment-168550
Thanks Daniel. "Simple actuarial statistics does not prove the wear-and-tear theory" Do you mean that actuarial statistics contradict the wear-and-tear theory? If so, you are incorrect: quite a f...
https://lemire.me/blog/2015/06/09/aging-software-bug/#comment-168543
@de Grey I should start by saying that I am very happy that you are doing the work you are doing. You are NOT correct that I was dismissed from my job at Cambridge, nor that I was a computer...
https://lemire.me/blog/2015/06/09/aging-software-bug/#comment-168533
@John Andersen What is abundantly clear is that the only likely cause for this increasing risk of mortality is the accumulation of junk in the body and the genetic damage to our DNA which bui...
https://lemire.me/blog/2015/06/09/aging-software-bug/#comment-168532
Excuse the typos in the last posting I guess it's what happens using an iPad in a moving boat! Regardless I needed to throw in my comments.
https://lemire.me/blog/2015/06/09/aging-software-bug/#comment-168530
Personally I am confident that Aubrey de Grey is very much on the right track. The evidence that he is correct is significant and research is increasing supporting much of the research for exampl...
https://lemire.me/blog/2015/06/09/aging-software-bug/#comment-168528
My attention was just drawn to this thread. Daniel, let me clarify a few points: - You are correct that I have had no more experience of bench research than, for example, Francis Crick. It's only...
https://lemire.me/blog/2015/06/09/aging-software-bug/#comment-168325
@Anonymous It is entirely fair to dismiss my opinions. Please do so. But what you just did has a name : https://en.wikipedia.org/wiki/Argument_from_authority The fact that I am not a subject expe...
https://lemire.me/blog/2015/06/09/aging-software-bug/#comment-167338
"My own theory, after reading avidly on the topic for several days, is that we were simply not designed by evolution to live past 40." So you dismiss people (such as Aubrey) who has a PhD in biol...
https://lemire.me/blog/2015/06/09/aging-software-bug/#comment-167222
I agree 20/30 years would be very ambitious to prevent the aging from arising but I feel confident we will be able to apply effective rejuventive interventions to remove the majority of the damag...
https://lemire.me/blog/2015/06/09/aging-software-bug/#comment-166978
@John my guess is we will reach the stage of having a decisive level of control over the aging process within 20/30 years. That sounds a tad optimistic to me. But what do I know? We ...
https://lemire.me/blog/2015/06/09/aging-software-bug/#comment-166962
A great article which goes along pretty much with my way of thinking because as I see it there are five technologies which will ultimately lead to radical life extension during the course of this...
https://lemire.me/blog/2015/06/09/aging-software-bug/#comment-166952
@Tom I know you are joking, but I am not convinced it is so simple. We do not know what consciousness is. We know it can be suspended and resumed (through sleep), but we do not know what it is. W...
https://lemire.me/blog/2015/06/09/aging-software-bug/#comment-166865
You are wrong. Conceptually, it is very easy to defeat death. Back up your mindfile each PM and, in the event of a "hardware crash" (AKA death), get your best friend to boot up a cyborg with your...
https://lemire.me/blog/2015/06/09/aging-software-bug/#comment-166863
Thank you Daniel, very interesting observations. I spent entire day reading about naked mole rats and I hope that one day our bodies will be modified to live a long and healthy life, just like na...
https://lemire.me/blog/2015/06/09/aging-software-bug/#comment-165803
@Anton Naked mole rats eventually age in a way that leads to a quick death, but not in a manner that is comparable to us. They remain young and healthy almost until the very end. So it is better ...
https://lemire.me/blog/2015/06/09/aging-software-bug/#comment-165465
Bryant: Nexus 6. Roy Batty. Incept date 2016. Combat model. Optimum self-sufficiency. Probably the leader. This is Zhora. She's trained for an off-world kick-murder squad. Talk about beauty and t...
https://lemire.me/blog/2015/06/09/aging-software-bug/#comment-165443
I'm curious where did you find that naked mole rats do not age ? It is true that they do not get cancer, do not feel pain and live up to 30 times longer that other rats, but they do die eventuall...
https://lemire.me/blog/2015/06/09/aging-software-bug/#comment-165414
On the SciFi aging point: Robert Heinlein had defeating aging as a theme in many of his books. In societies where some characters could defeat againg but the ability was not widespread they had t...
https://lemire.me/blog/2015/06/09/aging-software-bug/#comment-165413
@Derek R Evidently, even if you got rid of aging, people would still die of cancer and other diseases. This being said... Few people die of cancer in their 20s. The reason so many people die of h...
https://lemire.me/blog/2015/06/09/aging-software-bug/#comment-165384
The leading cause of death today is cancer (29%), so they would have to find a cure for cancer, before finding a cure for aging.
https://lemire.me/blog/2015/06/09/aging-software-bug/#comment-165328
@trylks - we have accelerating returns and the future progress is underestimated, but so are the challenges. We also have an exponential fiction, the gap between SciFi and science grows expon...
https://lemire.me/blog/2015/06/09/aging-software-bug/#comment-165326
I didn't read everything because I'm quite familiar with all of it. I became aware of these ideas through the idea of "technological singularity". I like AI a lot and I think it's going to dramat...
https://lemire.me/blog/2015/06/09/aging-software-bug/#comment-165319