What you need to know Slynd is a progestogen-only pill (POP) consisting of twenty-four tablets containing drospirenone 4mg and four inactive tablets in each 28-day cycle. Drospirenone is deri...
Abstract OVERVIEW OF: Copaescu AM, Vogrin S, James F, et al. Efficacy of a clinical decision rule to enable direct oral challenge in patients with low-risk penicillin allergy: The PALACE random...
Summary Drug-induced liver injury (DILI) is the leading cause of acute liver failure in high-income countries. Acute cholestasis is one of the most common forms of hepatotoxicity induced by azat...
Abstract OVERVIEW OF: Bhasin S, Lincoff AM, Nissen SE, et al. Effect of testosterone on progression from prediabetes to diabetes in men with hypogonadism: a substudy of the TRAVERSE randomized ...
Abstract OVERVIEW OF: Medicines and Healthcare products Regulatory Agency. Valproate (Belvo, Convulex, Depakote, Dyzantil, Epilim, Epilim Chrono or Chronosphere, Episenta, Epival and Syonell): ...
Abstract OVERVIEW OF: Hanula R, Bortolussi-Courval É, Mendel A, et al. Evaluation of oseltamivir used to prevent hospitalization in outpatients with influenza: a systematic review and meta-ana...
Knowledge of the harmful effects of medicines is limited at the point at which market authorisation is granted, with safety data based on a median of 1044 patients exposed in premarket studies of...
Management of type 2 diabetes has now been simplified by the understanding that the condition is caused by excess fat in the liver together with suppression of beta cell function by the associate...
Abstract OVERVIEW OF: Li RHW, Lo SST, Gemzell-Danielsson K, et al. Oral emergency contraception with levonorgestrel plus piroxicam: a randomised double-blind placebo-controlled trial . Lancet. ...
Abstract OVERVIEW OF: Danbury G Susan Gladstone: Prevention of future deaths report , 2023. Available: https://www.judiciary. uk/prevention-of-future-death-reports/susan-gladstone-prevention-of...
Abstract OVERVIEW OF: Lincoff AM, Brown-Frandsen K, Colhoun HM, et al. Semaglutide and cardiovascular outcomes in obesity without diabetes. N Engl J Med 2023;389:2221-32
The history of drug bulletins is closely linked with the consumer movement of the late 1950s and early 1960s. The first independent drug bulletin, The Medical Letter on Drugs and Therapeutics, wa...
In conjunction with BMJ Case Reports, DTB will feature occasional drug-related cases that are likely to be of interest to readers. These will include cases that involve recently marketed drugs fo...
Abstract OVERVIEW OF: Medicines and Healthcare products Regulatory Agency. Omega-3-acid ethyl ester medicines (Omacor/Teromeg 1000 mg capsules): dose-dependent increased risk of atrial fibrilla...
Introduction The rights of general practitioners (GPs) to prescribe medicines to their patients in the context of the National Health Service (NHS) in England have been well described.1 2 There ...
Abstract OVERVIEW OF: Neligan A, Adan G, Nevitt SJ, et al. Prognosis of adults and children following a first unprovoked seizure. Cochrane Database Syst Rev. 2023:10.1002/14651858.CD013847.pub2...
Abstract OVERVIEW OF: McQuilten ZK, Thao LTP, Pasricha SR, et al. Effect of low-dose aspirin versus placebo on incidence of anemia in the elderly: a secondary analysis of the aspirin in reducin...
Abstract OVERVIEW OF: Siraj RA, Bolton CE, McKeever TM. Association between antidepressants with pneumonia and exacerbation in patients with COPD: a self-controlled case series (SCCS). Thorax. ...
Abstract OVERVIEW OF: Medicines and Healthcare products Regulatory Agency. Fluoroquinolone antibiotics: reminder of the risk of disabling and potentially long-lasting or irreversible side effec...
In conjunction with BMJ Case Reports, DTB will feature occasional drug-related cases that are likely to be of interest to readers. These will include cases that involve recently marketed drugs fo...
In September 2023, NHS England issued a national safety alert in response to shortages of methylphenidate, lisdexamfetamine and guanfacine. This followed on from supply problems already being exp...
Acne vulgaris is very common and can have significant negative impact on people. While sometimes a transient problem, acne may persist for many years and often leads to permanent scars or pigment...
In conjunction with BMJ Case Reports, DTB will feature occasional drug-related cases that are likely to be of interest to readers. These will include cases that involve recently marketed drugs fo...
Abstract OVERVIEW OF: Florez MA, Jaoude JA, Patel RR, et al. Incidence of primary end point changes among active cancer phase 3 randomized clinical trials.JAMA Netw Open2023;6:e2313819.
Abstract OVERVIEW OF: Medicines and Healthcare products Regulatory Agency. Statins: very infrequent reports of myasthenia gravis.Drug Safety Update 2023;17(2):1.
Abstract OVERVIEW OF:Dequin PF, Meziani F, Quenot JP, et al. Hydrocortisone in severe community-acquired pneumonia. N Engl J Med 2023;388:1931–41.
Evidence that continuity of care improves important health outcomes has been building over the last three decades, strengthening in quality and reliability in the last few years. Continuity of ca...
Over 200 health journals call on the United Nations (UN), political leaders and health professionals to recognise that climate change and biodiversity loss are one indivisible crisis and must be ...