The mitochondrial calcium uniporter (MCU) is a transmembrane protein facilitating the entry of calcium ions into mitochondria from the cell cytosol. Maintaining calcium balance is crucial for enh...
https://cancerci.biomedcentral.com/articles/10.1186/s12935-024-03327-z
Hydrogen sulfide (H2S) is a significant endogenous mediator that has been implicated in the progression of various forms of cancer including breast cancer (BC). Cystathionine-β-synthase (CBS), c...
https://cancerci.biomedcentral.com/articles/10.1186/s12935-024-03317-1
Exosomes derived from tumor cells contribute to the pathogenesis of cancers. Metformin, the most usually used drug for type 2 diabetes, has been frequently investigated for anticancer effects. He...
https://cancerci.biomedcentral.com/articles/10.1186/s12935-024-03312-6
N6-methyladenosine (m6A) is important in regulating mRNA stability, splicing, and translation, and it also contributes to tumor development. However, there is still limited understanding of the c...
https://cancerci.biomedcentral.com/articles/10.1186/s12935-024-03307-3
Immunogenic cell death (ICD) is closely related to anti-tumor therapy and regulates the tumor microenvironment (TME). This study aims to explore the molecular characteristics of ICD in acute myel...
https://cancerci.biomedcentral.com/articles/10.1186/s12935-024-03326-0