The authors showed that the hyperactivation of Janus kinase 2 by the V617F mutation phosphorylated tyrosine residues in coactivator-associated arginine methyltransferase 1 (CARM1), an important ...
Researchers investigated the clinical consequences of a genetic predisposition toward lower white blood cell (WBC) counts among 89,559 biobank participants from tertiary care centers using a pol...
Investigators reported that expression of tricarboxylic acid cycle enzyme succinate-CoA ligase SUCLG1 strongly correlated with electron transport chain genes across various TCGA cancer transcrip...
Researchers defined the genomic binding sites of PML::RARA in primary mouse and human hematopoietic progenitor cells with V5-tagged PML::RARA, using anti-V5-PML::RARA chromatin immunoprecipitati...
In this retrospective study, allogeneic blood and marrow transplantation (alloBMT) recipients age 60 and older with lymphoid malignancies were included. Among 97 consecutive patients who receive...
A drug-like small molecule, SMS121, was identified by receptor-based virtual screening and experimentally demonstrated to target the lipid uptake protein CD36.
To understand how miR-214 aggravated oxidative stress in thalassemia erythroid cells, the authors investigated the molecular mechanism of miR-214 and its regulation of the oxidative status in th...
Germline gain-of function (GOF) SAMD9/SAMD9L mutations cause different syndromes with predisposition to myeloid neoplasms in the young. Primary somatic compensation mutations in the blood are ve...
The DKMS Stiftung Leben Spenden has honoured CIBSS member Prof. Dr Robert Zeiser for his outstanding research work in the field of allogeneic stem cell transplantation.
Researchers demonstrated the feasibility of incorporating multisector sampling in cancer vaccine design and provided information on the clinical applicability of clonality, distribution, and immu...
The authors revealed seven distinct immune cell types including myeloid-derived suppressor cells in the CD11bmidLy6Cmid cells, while CD11bhiLy6Chi cells included mostly monocytes/macrophages wit...