A Canadian-led study has identified genes which may be partially responsible for the development of cerebral palsy.
https://medicalxpress.com/news/2024-03-genetic-cerebral-palsy-uncovered-genome.html
Germline cancer-predisposition variants (CPVs) can be helpful in predicting risk in some pediatric cancers. However, CPV risk association in children with rhabdomyosarcoma has not been well studi...
https://medicalxpress.com/news/2024-03-cancer-predisposition-variants-adverse-outcomes.html
A team led by researchers at Weill Cornell Medicine has identified important drivers of the transformation of a type of blood cancer called follicular lymphoma from a slow-growing form to the agg...
https://medicalxpress.com/news/2024-03-discovery-strategy-follicular-lymphoma.html
An international team of researchers has found that the amount of protein consumed by pregnant women can impact the facial development of their offspring. In their study, published in the journal...
https://medicalxpress.com/news/2024-03-amount-protein-consumed-pregnant-women.html
A single genetic test could potentially replace the current two-step approach to diagnosing rare developmental disorders in children. This shift could enable earlier diagnoses for families and sa...
https://medicalxpress.com/news/2024-03-genomic-rare-genetic-diseases.html
Regulators of gene expression are thought to play an outsized role in disorders from cancers to heart disease. But how exactly do variations in gene regulation translate into a disease's biology?
https://medicalxpress.com/news/2024-03-scientists-closer-pulmonary-fibrosis-genetics.html
Researchers at the University of Cambridge have created the world's largest catalogue of human breast cells, which has revealed early cell changes in healthy carriers of BRCA1 and BRCA2 gene muta...
https://medicalxpress.com/news/2024-03-exhausted-immune-cells-healthy-women.html
An analysis of how brains with different forms of autism develop has revealed common underlying mechanisms that may respond to existing medications.
https://medicalxpress.com/news/2024-03-autism-mechanism-drugs.html
Persons with a higher genetic risk of obesity need to work out harder than those of moderate or low genetic risk to avoid becoming obese, according to a Vanderbilt University Medical Center (VUMC...
https://medicalxpress.com/news/2024-03-higher-genetic-obesity-harder-results.html
Take a puff of nicotine for the first time, and your DNA plays an important role, alongside social and environmental factors, in shaping what happens next.
Researchers have uncovered two novel gene mutations that may be responsible for a rare blood disorder. The mutations are found on the GNE gene and impact an enzyme, also called GNE, that is invol...
https://medicalxpress.com/news/2024-03-mutations-rare-blood-disorder.html
Researchers at Weill Cornell Medicine have discovered a protein called SEL1L that plays a critical role in clearing collagen from tissue, and that may be a therapeutic target to help prevent fibr...
https://medicalxpress.com/news/2024-03-protein-sensor-plays-role-lung.html
Brain development is a highly orchestrated process involving numerous parallel and sequential steps. Many of these steps depend on the activation of specific genes. A team led by Christian Mayer ...
https://medicalxpress.com/news/2024-03-developmental-crossroads-brain-proteins-nerve.html
A new study has shown that risk scores based on our genes and gut bacteria can improve the prediction of diseases such as type 2 diabetes and prostate cancer over traditional risk factors alone.
https://medicalxpress.com/news/2024-03-genes-gut-bacteria-early-diseases.html
A research team from the Paul-Ehrlich-Institut has gained important insights into the role of the human guanylate-binding protein 1 (GBP1) in hepatitis C virus infection. Their results show that ...
https://medicalxpress.com/news/2024-03-hepatitis-virus-infection-team-protein.html
Acute lymphoblastic leukemia (ALL), the most common childhood cancer, disproportionately affects children of Hispanic/Latino origin in the United States. They are 30–40% more likely to get ALL ...
https://medicalxpress.com/news/2024-03-genetic-variant-contributing-disparities-childhood.html
Nasopharyngeal carcinoma (or NPC) is a rare type of cancer affecting the epithelial tissue of the nasopharynx, the upper part of the throat behind the nasal cavity. Among the three main subtypes ...
https://medicalxpress.com/news/2024-03-unravel-mechanisms-epstein-barr-virus.html
To what extent are exceptional human achievements influenced by genetic factors? This question, dating back to the early days of human genetics, seems to be easier to address today as modern mole...
https://medicalxpress.com/news/2024-03-music-genomes-beethoven-genes.html
University of Queensland researchers have developed a method to predict if a child is likely to develop sepsis and go into organ failure.
https://medicalxpress.com/news/2024-03-blood-analysis-sepsis-failure-children.html
Brazilian and American researchers have identified 87 genes linked to alterations in blood pressure and 144 others associated with variations in heart rate. The findings, published in the journal...
https://medicalxpress.com/news/2024-03-rodents-key-genes-blood-pressure.html
Researchers at the USC Leonard Davis School of Gerontology have discovered a genetic mutation in a small mitochondrial protein that may promote longevity, preserve cognitive function, and protect...
https://medicalxpress.com/news/2024-03-newly-beneficial-mutation-mitochondrial-dna.html
A gene associated with colorectal cancer appears to also play a role in the development of other solid tumors, according to a study of over 350,000 patient biopsy samples conducted by researchers...
https://medicalxpress.com/news/2024-03-colorectal-cancer-gene-implicated-broad.html
New research from scientists at the Wu Tsai Neurosciences Institute at Stanford University has identified a key driver of myelination, the formation of protective fatty sheaths around nerve fiber...
https://medicalxpress.com/news/2024-03-scientists-key-driver-myelin.html
Research by Victor Ambros, Ph.D., provides new insights into a recently identified class of neurodevelopmental disorders called Argonaute syndromes. Dr. Ambros and colleagues believe their Procee...
https://medicalxpress.com/news/2024-03-reveals-argonaute-syndromes-class-neurodevelopmental.html
Scientists from The Australian National University (ANU) have discovered a gene mutation is responsible for causing psoriasis—a chronic inflammatory skin disease that causes patients to develop...
https://medicalxpress.com/news/2024-03-gene-discovery-people-chronic-skin.html
Scientists have identified a new method of analyzing genomic data in a major discovery that means patients with unexplained kidney failure are finally getting a diagnosis.
https://medicalxpress.com/news/2024-03-genomic-method-diagnosis-patients-unexplained.html
Researchers at the Francis Crick Institute have shed light on the proteins controlling the development of ovaries in mice before and after birth. This could lead to a better understanding of how ...
https://medicalxpress.com/news/2024-03-uncover-protein-interactions-fertility-female.html
Amyotrophic lateral sclerosis (ALS) is a degenerative disease. The neurons responsible for movement begin to die and muscle control is progressively lost, leading to a fatal outcome. The causes o...
https://medicalxpress.com/news/2024-03-accumulation-junk-proteins-aging-source.html
A new study led by the University of California, Irvine, has revealed a potential shift in our basic knowledge of the origins of birth defects, which affect about 3% of babies born in the United ...
https://medicalxpress.com/news/2024-03-secrets-birth-defect-early-strategies.html
Scientists from Duke-NUS Medical School have identified a gene that plays a crucial role in regulating energy supply to cells that drive kidney failure. This discovery concerning the gene named W...
https://medicalxpress.com/news/2024-03-scientists-powerhouse-gene-doors-treatments.html