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U.S. FDA approves Pfizer's BEQVEZ™ (fidanacogene ela...ec-dzkt), a one-time gene therapy for adults with Hemophilia B
Pfizer Inc. (NYSE: PFE) announced today that the U.S. Food and Drug Administration (FDA) has approved BEQVEZ™ (fidanacogene elaparvovec-dzkt) for the treatment of adults with moderate to sever...
AskBio receives FDA Fast Track Designation for AB-1002 investigational gene therapy program in congestive heart failure
Bayer AG and Asklepios BioPharmaceutical, Inc. (AskBio), a gene therapy company wholly owned and independently operated as a subsidiary of Bayer AG, announced that the U.S. Food and Drug Adminis...
Researchers publish final results of key clinical trial for gene therapy for sickle cell disease
In a landmark study, an international consortium led by researchers at Children's Hospital of Philadelphia (CHOP) published the final results of a key clinical trial of the gene therapy CASGEVY (...
Optimal timing maximises Paxlovid benefits for treating COVID-19
Researchers have described the optimal timing for COVID-19 patients to take the antiviral, Paxlovid, to get the most benefit from the treatment, according to a study published April 16 in eLife. ...
European Commission approves Pfizer's EMBLAVEO® for p...h multidrug-resistant infections and limited treatment options
Pfizer Inc. (NYSE: PFE) today announced that the European Commission (EC) has granted marketing authorization for EMBLAVEO® (aztreonam-avibactam) for the treatment of adult patients with compli...
Researchers develop a new way to safely boost immune cells to fight cancer
Cancer is the monster of our society. Last year alone, more than 600,000 people in the United States died from cancer, according to the American Cancer Society. The relentless pursuit of understa...
How the Birmingham Drug Discovery Hub created an investment-ready 'drug library'
A novel approach to drug discovery is enabling University of Birmingham researchers to overcome the 'valley of death', where projects fail due to the funding gap between original research and com...
Common HIV treatments may aid Alzheimer's disease patients
Alzheimer's disease (AD) currently afflicts nearly seven million people in the U.S. With this number expected to grow to nearly 13 million by 2050, the lack of meaningful therapies represents a m...
AskBio presents 18-month Phase Ib trial results of AB-1005 gene therapy for patients with Parkinson's disease
Bayer AG and Asklepios BioPharmaceutical, Inc. (AskBio), a gene therapy company wholly owned and independently operated as a subsidiary of Bayer AG, on Sunday April 14 presented results from the...
Next-generation treatments hitch a ride into cancer cells
Antisense oligonucleotides (ASOs) are next-generation drugs that can treat disease by blocking the transfer of harmful messages from our genes. In people with cancer, ASOs have the potential to b...
Groundbreaking treatment approach shows promise in hard-to-treat cancers
Researchers have developed a functional precision medicine approach that targets cancer by combining genetic testing with a new way to test individual drugs on tumor samples. The results of the c...
This outdated diabetes drug still has something to offer
Thiazolidinediones (TZDs) are a class of drug that can be used to treat type 2 diabetes by reversing insulin resistance, one of the main hallmarks of the disease. While TZDs were extremely popula...
New drug prevents flu-related inflammation and lung damage
Infection with the influenza virus leads to lung injury through inflammation over-activation that causes collateral damage to cells required for breathing. Such damage can be life-threatening, bu...
Swapping red meat for herring/sardines could save up to 750,000 lives/year in 2050
Swapping red meat for 'forage fish', such as herring, sardines, and anchovies, could save up to 750,000 lives a year in 2050 and significantly reduce the prevalence of disability as a result of d...
Does cannabis use affect cognitive decline?
A new study by Upstate Medical University researchers shows that recreational cannabis use may offer protection against cognitive decline. The study, done by Master of Public Health (MPH) stud...
https://www.worldpharmanews.com/research/6555-does-cannabis-use-affect-cognitive-decline
Novel biological mechanism discovered that could lead to new treatments for neurological disorders, cancers
The lab of Yongchao C. Ma, PhD, at Stanley Manne Children's Research Institute at Ann & Robert H. Lurie Children's Hospital of Chicago discovered a fundamental biological mechanism that could lea...
New study paves the way for precision drugs to treat blood cancers
The Janus kinase 2 (JAK2) protein mediates signaling from several cytokine receptors in the regulation of hematopoiesis and immune responses. Somatic mutations in human JAK2 lead to constitutive ...
Johns Hopkins investigators develop novel treatment for T-cell leukemias and lymphomas
A novel treatment for leukemias and lymphomas that arise from immune system T cells, developed by investigators at the Johns Hopkins Kimmel Cancer Center and its Ludwig Center and Lustgarten Labo...
Scientists link certain gut bacteria to lower heart disease risk
Changes in the gut microbiome have been implicated in a range of diseases including type 2 diabetes, obesity, and inflammatory bowel disease. Now, a team of researchers at the Broad Institute of ...
Mayo Clinic scientists pioneer immunotherapy technique for autoimmune diseases
Mayo Clinic scientists have developed an immunotherapy strategy that potentially lays the groundwork for treating a spectrum of autoimmune diseases. The new technique, detailed in a preclinica...