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- Feed Preview This Week in Parasitism
TWiP 233: Cryptosporidium not cryptocurrency
TWiP solves the case of the physician with no significant previous medical history who is currently doing their fellowship training develops diarrhea, and presents a new clinical case for our ast...
TWiP 232: Lives of Wolbachia
TWiP reviews the cellular lives of Wolbachia, a gram-negative bacteria that infects many arthropods and filarial nematodes with very different outcomes – parasitism or mutualism. Hosts: Dick...
TWiP 231: Scotch in drink and tape
TWiP solves the case of the Woman With White Worms, and presents a new clinical case to decipher. Hosts: Vincent Racaniello , Dickson Despommier , Daniel Griffin , and Christina Naula Su...
TWiP 230: Healing cutaneous leishmaniasis with Maria Adelaida Gomez
Maria Adelaida Gomez joins TWiP to discuss her career and the work of her laboratory on understanding the healing process during cutaneous leishmaniasis. Hosts: Vincent Racaniello , Dickson D...
TWiP 229: The very hungry flatworm
Eyal joins TWiP to solve the case of the Female Traveler with Intermittent Fever and Ring Enhancements in the Liver. Hosts: Vincent Racaniello , Dickson Despommier , Daniel Griffin , and Ch...
TWiP 228: Parasitic fountain of youth
TWiP discusses a tapeworm that causes extreme lifespan extension in infected ant workers, and a candidate antibody drug for prevention of malaria. Hosts: Vincent Racaniello , Dickson Despommi...
TWiP 227: Alpha-gal syndrome
Jim Small joins TWiP to solve the case of the 41 year old Man with sudden GI distress and itchy hives, followed by a discussion of parasites and childhood stunting. Hosts: Vincent Racaniello ,...
TWiP 226: Successful systems attract parasites
TWiP reviews some parasite stories of 2023, including progress in the control of malaria and polio, and review a connection between parasites and childhood stunting. Hosts: Vincent Racaniello ...
TWiP 225: Wandering worm with Lee Gottesdiener
Lee Gottesdiener joins TWiP to help solve the case of the 46 Year Old Man with Ongoing Upper Extremity Swelling, and review plant‑based production of a protective vaccine antigen against the bo...
TWiP 224: Neglected tropical diseases roadmap with Chuck Knirsch
Chuck Knirsch returns to TWiP to discuss the Neglected Tropical Diseases Roadmap published by WHO, which sets global targets and milestones to prevent, control, eliminate or eradicate 20 diseases...
TWiP 223: Voluminous diarrhea
TWiP solves the case of the Haitian female with AIDS and voluminous diarrhea, and review the pathogenesis, epidemiology, prevention and treatment of malaria and Chagas disease. Hosts: Vincent ...
TWiP 222: Balamuthia in the brain with Natasha Spottiswoode
At the meeting of the American Society for Tropical Medicine and Hygeine in Chicago, Natasha joins TWiP to solve the case of the Man with a Generalized Seizure and Infectious Forms in the Brain. ...
TWiP 221: Delusional parasitosis
Michelle and Alexander join TWiP to solve their case of the 36 Year Old Male with shortness of breath, stinging pain in the extremities, fatigue, abdominal cramps, and bowel irregularities, and d...
TWiP 220: Denies any bug bites
TWiP solves the case of the Hiker from Queens who Denies Bug Bites, and reveal two different malaria experimental vaccines that target different parts of the parasite life cycle. Hosts: Vincen...
TWIP 219: Sick as a dog
TWiP solves the case of the 19 month old Female Having Issues, and discusses the finding that selection for insecticide resistance can promote Plasmodium falciparum infection in Anopheles mosq...
TWiP 218: Malaria parasite evades mosquito
TWiP solves two cases this week, the Man with Issues after COVID-19, and the Man with Left Arm Weakness, then describe how the malaria parasite evades mosquito immunity by glutaminyl cyclase–me...
TWiP 217: ChatGPT solves the case
TWiP solves the case of the Man With Dog Exposure, and discuss rapid and spontaneous post-partum clearance of Plasmodium falciparum related to expulsion of the placenta. Hosts: Vincent Racani...
TWiP 216: A challenging case
Eyal joins TWiP to solve the case of the case of the Feverish Patient from Israel, and reveals his training and experience with travel medicine in Israel. Hosts: Vincent Racaniello , Dickson ...
TWiP 215: A mobile piece of spaghetti
TWiP solves the case of the case of the boy in Uganda with a mobile piece of spaghetti in the gallbladder, and reviews papers on female genital schistosomiasis in rural Madagascar, and a volatile...
TWiP 214: Tropical medicine excursions with Kay Schaefer
Kay Schaefer joins TWiP to solve the case of the German Male with Hematuria, and discusses Tropical Medicine Excursions, which provides patient-oriented training courses for healthcare profession...
TWiP 213: One deadly snail with Jessie Stone, MD
Jessie Stone joins TWiP to solve the case of the Boy With a Swollen Belly, and discusses Soft Power Health, a clinic that she founded in Uganda to provide healthcare for people in need. Hosts:�...
TWiP 212: The Man from Mali with Shauna Gunaratne
Shauna Gunaratne joins TWiP to solve the case of the Man from Mali with Painless Skin Lesions, and discuss her plans for a tropical medicine institute in New York City. Hosts: Vincent Racaniel...
TWiP 211: Monoclonal against malaria in Mali
TWiP solves the case of the Man from Hong Kong with Multiple Comorbidities, and discuss safety and efficacy of a monoclonal antibody against malaria in Mali. Hosts: Vincent Racaniello , Dickso...
TWiP 210: Is there a doctor on board? with Aisha Khatib
From ASTMH2022 in Seattle, Aisha joins the TWiP team to talk about her training and her career, including delivering a baby on an airplane, and they solve the Case of the Heartsick Guatemalan Sep...
TWiP 209: A worm in paradise
The TWiP team solves the case of the Woman From Hawaii With Allodynia and abdominal pain, bilateral hip and leg pain, dizziness, and diffuse hyperesthesia. Hosts: Vincent Racaniello , Dickson ...
TWiP 208: A red herring
The TWiP team solves the case of the Woman Who Vomited Up a Worm, and discuss how malaria transmission intensity can modify the effectiveness of the RTS, S/AS01 vaccine in Africa. Hosts: Vince...
TWiP 207: Accidental host with Claire Panosian, MD
Claire joins the TWiP team to discuss her training and experience as an infectious disease physician, and her transition to science communication, then we solve the case of the Honduran Male with...
TWiP 206: Bacteria protect mosquitoes from parasites
The TWiP team solves the case of the Ghanian Women With Leg Swelling, and relate how Anopheline mosquitoes are protected against parasite infection by tryptophan catabolism in gut microbiota. H...
TWiP 205: Two for the price of one
The TWiP team solves the case of the Pregnant Ghanian Living Near a River, and reveal emodepside, a drug for treatment of onchocerciasis. Hosts: Vincent Racaniello , Dickson Despommier , Dani...
TWiP 204: Near a fast-flowing river
The TWiP team solves the case Two Ghanians Near A Fast-Flowing River, and discuss a promising new drug for treatment of African trypanosomiasis. Hosts: Vincent Racaniello , Dickson Despommier ...
TWiP 203: True, true, and unrelated
The TWiP team solves the case of the Shopkeeper with Thirst, Rash, and low Blood Oxygen, then review a study on the effect on survival to adulthood in Tanzania of mosquito net use in early childh...
TWiP 202: 80 microns and ovoid
Sara from the Febrile Podcast joins the TWiP team at The Incubator to solve the case of the Man With an Egg Laden Colonic Mass, and Daniel presents a new puzzle for us to solve. Hosts: Vincent...
TWiP 201: Tiny and hairy
The TWiP team solves the case of the Man with a Cat and Ring Enhancing Lesions, and discuss domestic mammals as reservoirs for Leishmania donovani on the Indian subcontinent. Hosts: Vincent Ra...
TWiP 200: Parasites without borders
The TWiP team solves the case of the Gentleman from New York with Intestinal Issues, and review a 20 year study of butterflies, their associated parasitoid wasp and Wolbachia introduced into an i...
TWiP 199: Chagas kisses Cruzi and Brucei bites
The TWiP team solves the case of the Traveler to Tanzania with a Purple Lesion, and discuss Mosquirix, the first vaccine approved for Plasmodium parasites. Hosts: Vincent Racaniello , Dickson ...
TWiP 198: Cyclospora in the dining room with the salad bar
The TWiP quadfecta solves the case of the Traveler With Watery Diarrhea, and reveals that a heat-shock response regulated by a transcription factor protects human malaria parasites from the high ...
TWiP 197: An adventurous eater
TWiP solves the case of the Adventurous Eater with Areas of Swelling, and discusses an experimental Trypanosoma vivax vaccine comprising an invariant flagellum antigen. Hosts: Vincent Racaniel...
TWiP 196: Naked eye entomologist
TWiP solves the case of the Homeless Man With Skin Issues, and discusses an experimental mRNA based malaria vaccine. Hosts: Vincent Racaniello and Daniel Griffin Download TWiP #196 (49 ...
TWiP 195: Shocking diseases in attractive NY accents
Christina returns to the TWiP trifecta to solve the case of the Beachgoer with Red Lines on Her foot, and an experimental malaria vaccine based on the junctional region of the circumsporozoite pr...
TWiP 194: Eye had a corneal scraping
TWiP solves the case of the Long Island Man with Unilateral Eye Pain, followed by a discussion of how enteric helminth coinfection enhances host susceptibility to West Nile virus by a tuft cell-I...
TWiP 193: A serpiginous trail
Audun returns to help solve the case of the Ecuadorean Gentleman Treated for COVID-19, followed by a discussion of the interaction of Blastocystis with the intestinal microbiota and the immune sy...
TWiP 192: Towel off vigorously
The TWiPers solve the case of the Teenager in Malawi with Red Urine, then Audun joins to present our clinical case for this episode. Hosts: Vincent Racaniello , Dickson Despommier , and Danie...
TWiP 191: Dickson's ocular anomaly
The TWiPers solve the case of the Rural Man from North Carolina with Blurred Vision, and discuss the results of single-cell RNA sequencing of Schistosoma mansoni. Hosts: Vincent Racaniello , D...
TWiP 190: But Doc, what could it be?
Christina from Glasgow returns to help the TWiPlets solve the case of the Ghanian Woman with Abdominal Mass, followed by discussion of the impact of COVID-19 on malaria morbidity and mortality in...
TWiP 189: Toe jammin'
Christina from Glasgow joins the TWiPlets to solve the case of the Elderly Gentlemen with Full Body Rash, and to present a new clinical case for listeners to solve. Hosts: Vincent Racaniello , ...
TWiP 188: Terrible tropisms
Dickson, Daniel and Vincent solve the case of the Baby with Hydrocephalus, and present a new clinical case for listeners to solve. Hosts: Vincent Racaniello , Dickson Despommier , and Daniel ...
TWiP 187: Granny's granuloma
Dickson, Daniel and Vincent solve the case of the Middle Aged Woman with Loss of Vision in One Eye, and discuss the role of heme oxygenase in the various protozoan infections. Hosts: Vincent R...
TWiP 186: Not rationing rationality
Dickson, Daniel and Vincent solve the case of the Elder Gardener Feeling Poorly, and discuss the three-dimensional ultrastructure of Plasmodium falciparum during cytokinesis. Hosts: Vincent Ra...
TWiP 185: Latrinalia
Dickson, Daniel and Vincent solve the case of the Wife of a Guy with Cyclospora Diarrhea, and discuss the discovery of an intrinsic oscillator that drives the bloodstream stage cycle of the malar...
TWiP 184: The hunter gets captured by the game
Dickson, Daniel and Vincent solve the case of the Safari Goer With Watery Diarrhea, and explain how a microsporidian endosymbiont of Anopheles mosquitoes might impair the transmission of malaria....
TWiP 183: When they dry they die
Dickson, Daniel and Vincent solve the case of the Female with Itchy Anus, and reveal the structure of a roundworm membrane protein involved in digestion of nutrients. Hosts: Vincent Racaniello...
TWiP 182: Super spreaders of science
Dickson, Daniel and Vincent solve the case of the Ugandan Volunteer With Morning Bites and discuss integration of HIV-1 into the Schistosome genome, with a sprinkling of COVID-19 throughout. Ho...
TWiP 181: Daniel's drive-through
Dickson, Daniel and Vincent solve the case of the Two Volunteers With Watery Diarrhea, discuss diagnosis of SARS-CoV-2 in the New York area, and reveal an approach to preventing honeybee colony c...
TWiP 180: A spleen palaver
The TWiP professors solve the case of the Ugandan Child with Splenomegaly, and reveal that mutations in the P. falciparum genome that confer artemisinin resistance interfere with endocytic uptake...
TWiP 179: Verminous visitors
The TWiP DVD solve the case of the Child Who Passed Worms, and discuss a non-human primate model for severe malarial anemia. Hosts: Vincent Racaniello , Dickson Despommier , and Daniel Griffi...
TWiP 178: The shadowlands of medicine
The Knights of the TWiP solve the case of the Man Who Lost Weight, and discuss a Plasmodium protein kinase that is a malarial drug target. Hosts: Vincent Racaniello , Dickson Despommier , and�...
TWiP 177: A scabrous education
The TWiPsters solve the case of the Rashy Schoolteacher, and reveal a drug from rotifers that live on the snail intermediate host which paralyzes schistosome cercariae and prevents infection of m...
TWiP 176: Blood schmear
The TWiPpers of the bite fantastic solve the case of the Indian Man Who Hiked, and discuss the effects of schistosome soluble egg antigen on infection of lymphocytes with HIV-1. Hosts: Vincent...
TWiP 175: None alone pathognomonic
The TWiP'ers solve the case of the Sudanese Boy With Fever, and reveal antibodies against that slow invasion of red blood cells potentiate other malaria-blocking antibodies. Hosts: Vincent Rac...
TWiP 174: Fat cat
Hosts: Vincent Racaniello , Dickson Despommier , and Daniel Griffin The TWiPloid organisms solve the case of the Doctor with Chronic Epigastric Pain, and reveal how levels of linoleic acid i...
TWiP 173: Rose colored spots
Hosts: Vincent Racaniello , Dickson Despommier , and Daniel Griffin The podcastellani hosts solve the case of the Sailor With Dysentery, and reveal the first virus discovered in Plasmodium ...
TWiP 172: A painless lesion
Hosts: Vincent Racaniello , Dickson Despommier , and Daniel Griffin The metacyclic TWiPomastigotes solve the case of the Child With a Painless Leg Lesion, and reveal how to kill mosquitoes w...
TWiP 171: Better than a sharp stick in the eye
The Leishmaniacs solve the case of the Child With Band Keratopathy, and reveal a eukaryotic parasite with functional mitochondria but without mitochondrial genomes. Hosts: Vincent Racaniello ,...
TWiP 170: A worm's eye view
The TWiPlicates solve the case of the Child With Retinal Granuloma, and discuss an association of the complement protein collectin-11 with the pathophysiology of Chagas disease. Hosts: Vincent...
TWiP 169: What goes on in the snail
The TriTWiPomonads solve the case of the Child Who Passed a Worm, and reveal recombination between bovine and human schistosome species. Hosts: Vincent Racaniello , Dickson Despommier , and D...
TWiP 168: Kleptoparasitism and the stercoraceous souvenir
The Giardians of the Galaxy solve the case of the Woman With a Colonic Stowaway from Hispaniola, and discuss activation of intestinal tuft cells by Trichinella spiralis. Hosts: Vincent Racanie...
TWiP 167: The constipated mathematician
The Tremendous Trio solve the case of the Woman With Foul Steatorrhea, and reveal breakdown of the glycocalyx associated with severe and fatal malaria. Hosts: Vincent Racaniello , Dickson Des...
TWiP 166: From remote locations
The Podfessors solve the case of the Teenager With Swollen Scrotum, and continue the story arc of Daniel's favorite cells, B-1 cells, and their association with protective immune responses in hu...
TWiP 165: The sound of crackles
The TWiP team solves the case of the Four Year Old with Fever, Headache, and Cough, and discuss the release of extracellular vesicles from Leishmania amazonensis that manipulate the host immune ...
TWiP 164: Surf n' perf
The TWiP legends solve the case of Surfer Sans Septum, and discuss how two symbiotic bacteria in the tsetse fly allow colonization with Trypanosoma brucei. Hosts: Vincent Racaniello , Dickson...
TWiP 163: Trout and parasites
The doctors of awesome solve the case of the Woman Who Visited Lebanon, and reveal that immunoglobulins protect the olfactory organ of trout against infection with the Ich parasite. Hosts: Vi...
TWiP 162: That swollen parcel of dropsies
The TWiP professors solve the case of the Baby With Pericardial Effusion, and discuss whether the flagellate without a flagella, Dientamoeba fragilis, causes human illness. Hosts: Vincent Raca...
TWiP 161: All I need is a bit of skin
The TWiPsters solve the case of the Brazilian Immigrant With Heart Problems, and describe how genome organization controls trypanosome antigenic variation. Hosts: Vincent Racaniello , Dickson...
TWiP 160: Toddy tappers
The TWiPlets solve the case of the Electrician from Tamil Nadu with a Liver Mass, and reveal that dogs and humans share a common Chadian Guinea worm. Hosts: Vincent Racaniello , Dickson Despo...
TWiP 159: Loa and Loa but not gone
The TWiP triptych solve the case of the 9/11 Survivor infested with parasites, and discuss the effect of community ivermectin treatment for onchocerciasis on Loa loa infections. Hosts: Vinc...
TWiP 158: Ant-appetising slime balls
The TWiP hosts solve the case of the Thai Woman With Red Bumps, and reveal that a master manipulator contacts ant brain tissue to control its behavior. Hosts: Vincent Racaniello , Dickson Des...
TWiP 157: What a long, strange TWiP it's been
The TWiP professors solve the case of the Woman With Intracellular Ring Forms, and explore the role of Coxiella and Rickettsia endosymbionts in acquisition of Babesia by ticks. Hosts: Vinc...
TWiP 156: The parasitic devil is in the details
The TWiP crew solves the case of the Ecuadorian with Immunodeficiency and Chronic Diarrhea, and discuss oral transmission of Chagas disease in mice. Hosts: Vincent Racaniello , Dickson Despom...
TWiP 155: Miss Dickson
Justin joins the TWiP team to solve the case of the Gentleman with B cell Lymphoma, and consider the finding of Dracunculus species in river otters from Arkansas. Hosts: Vincent Racaniello , ...
TWiP 154: A louse-y episode
Vincent and Daniel solve the case of the Man in the City with Groin Rash, catch up on the long backlog of email, and present a new case, possibly the most complex one yet on the show. Hosts: ...
TWiP 153: Ars longa, vita brevis
Vincent and Daniel solve the case of the Panamanian Farmer with Three Weeks of Diarrhea, and discuss how microbes egested during bites of sand flies exacerbate the severity of leishmaniasis. H...
TWiP 152: A range of rads
The TWiP peeps solve the case of the Panamanian Mother with Steatorrhea, and reveal new monoclonal antibodies that effectively block malarial infection. Hosts: Vincent Racaniello , Dickson De...
TWiP 151: Indiscriminate bulk feeders
The Podfessors solve the case of the Itchy Child from Panama, and discuss competition for blood in human malaria-helminth co-infections. Hosts: Vincent Racaniello , Dickson Despommier , and ...
TWiP 150: Fast food
The TWiPers solve the case of the Panamanian Man With Leg Ulcer, and describe how a crab predator preferentially feeds on parasite infected prey - even though the parasite makes them faster! H...
TWiP 149: Stranger in a strange land
Shivang joins the TWiP triumvirate to solve the case of the New Yorker With Rash and Pins and Needles, and reveal how agrochemicals increase risk of human schistosomiasis by causing high snail de...
TWiP 148: Weep and sweep
The TWiP-tologists solve the case of the South American Child With Belly Pain, and reveal how B1 cell IgE blocks parasite clearance by inhibiting mast cell activation by B2 cell IgE. Hosts: V...
TWiP 147: The savvy physician tests the tissue
The three amigos of parasitology solve the case of the New York Lawyer With A Foot Ulcer, and discuss a survey of rodents for the raccoon roundworm in California. Hosts: Vincent Racaniello , ...
TWiP 146: Thus misspake Despommier
The TWIPniks solve the case of the Man With Diarrhea and 100 Micron Objects In Stool, and discuss the reticulocyte receptor for Plasmodium vivax. Hosts: Vincent Racaniello , Dickson Despommie...
TWiP 145: Is it excreted or secreted?
The Estimados Profesores of TWIP solve the case of the Man With Motile Objects, and reveal the secreted and excreted proteins of Giardia parasites. Hosts: Vincent Racaniello , Dickson Despomm...
TWiP 144: A blood-free snip
The TWiPtomaniacs solve the case of the Boy With Visual Disturbances and Itching, and discuss identifying secreted and excreted proteins of Trichinella parasites. Hosts: Vincent Racaniello , D...
TWiP 143: There's a lot of worms out there
The TWiPians solve the case of the Woman With Anemia, Eosinophila, and a Worm in Her Intestine, and discuss a study on the function and druggability of two malarial aspartate proteases. Hosts:�...
TWiP 142: Just a virus, go home
The TWiPsids solve the case of the Guatemalan Positive for Rhinovirus, and reveal how to kill all African trypanosomes with a primate apolipoprotein. Hosts: Vincent Racaniello , Dickson Despom...
TWiP 141: Paratransgenesis
The TWiP Wataalamu solve the case of the One Year Old From Kenya With Moving Skin Lesions, and describe how to make mosquitoes refractory to Plasmodium with engineered symbiotic bacteria. Host...
TWiP 140: Blasting Blastocystis
The triple TWiP solve the case of the Peace Corp Veteran with Eosinophilia, and discuss the genome sequence of the hyper-prevalent parasitic eukaryote Blastocystis. Hosts: Vincent Racaniello ,...
TWiP 139: Eggsactly, ova and ova
The TWiPwalas solve the case of the Woman with a Worm in Her Eye, and discuss the role of nitric oxide in the resistance of rats to Schistosoma japonicum. Hosts: Vincent Racaniello , Dickson ...
TWiP 138: Telmophages and the skin parasite landscape
The TWiPsters solve the case of the Child from DR with Poppy Seed Sized Things On His Head Hair Shafts, and reveal how the skin parasite landscape determines the infectiousness of Leishmania. ...
TWiP 137: An aberrant encounter
The TWiPtoids solve the case of the Man from India with a Neck Lump, and explore the role of a transmissible dysbiotic skin microbiome in inflammation during cutaneous leishmaniasis. Hosts: Vi...
TWiP 136: Daniel throws a softball
The TWiP Titans solve the case of the Man from Queens with a Blister Burster, and explain the role of inflammatory monocytes during Leishmania infection of the skin. Hosts: Vincent Racaniello ...
TWiP 135: Embryonated eggs of wisdom
Dickson returns to the TWiP hosts to solve the case of the Woman from Colorado With Loose Stools, and explain how single-sex infection with female Schistosoma mansoni reduces hepatic fibrosis. ...
TWiP 134: Does toxoplasma make you sexy?
Daniel and Vincent solve the case of the Haitian Girl Who Failed To Thrive, and visit two studies that address the question of whether infection with Toxoplasma gondii alters human behavior. ...
TWiP 133: Tape test
Daniel and Vincent solve the case of the Woman With Anal Area Discomfort, and discuss the multiple functions of a clathrin adapter protein in formation of rhoptry and microneme secretory orga...
TWiP 132: Salted crab som tum
The TWiP-tastic peeps solve the case of the Thai Man Coughing Up Blood, and reveal potential therapies for trypanosomiasis that are inhibitors of protein import into glycosomes. Hosts: Vincen...
TWiP 131: Entomophagy
Jonathan from the podcast Arthro-Pod joins the TWiPerati to solve the case of the Peruvian Woman With Inguinal Insect Bite, and discuss warm autoimmune hemolytic anemic that develops after babe...
TWiP 130: Paige Turner
Hosts: Vincent Racaniello , Dickson Despommier , and Daniel Griffin The TWiPniks solve the case of the Man With AIDS, and explore how secretion of extracellular vesicles influences the ...
TWiP 129: Human kindness, river blindness
Hosts: Vincent Racaniello , Dickson Despommier , and Daniel Griffin The TWiP Masters solve the case of the Australian Wildlife Carer, and review evidence that nodding syndrome may be ca...
TWiP 128: It's over 9000!
Hosts: Vincent Racaniello , Dickson Despommier , and Daniel Griffin The TWiPerati solve the case of the Man Who Sat in Feces, and discuss a study on how Dickson's favorite parasite indu...
TWiP 127: Kava not Cava
Hosts: Vincent Racaniello , Dickson Despommier , and Daniel Griffin The TWiPsters solve the case of the Peace Corps Volunteer with a Liver Lesion, and discuss the dependence of Leishma...
TWiP 126: A virus walks into a parasite
Hosts: Vincent Racaniello , Dickson Despommier , and Daniel Griffin The TWiP Trinity solve the case of the Peace Corps volunteer with diarrhea, and reveal how immunizing against a virus...
TWiP 125: Third time's a charm
Hosts: Vincent Racaniello , Dickson Despommier , and Daniel Griffin The TWiPonderers solve the case of the Timber Worker with Severe Shaking Chills, and describe an experimental malar...
TWiP 124: RPAing with the tryps
Hosts: Vincent Racaniello , Dickson Despommier , and Daniel Griffin The prolific podcast-shedding Hosts solve the case of the Global Health Intern with a snakelike lesion on her foot, a...
TWiP 123: What we know is confusing
Hosts: Vincent Racaniello , Dickson Despommier , and Daniel Griffin The TWiPanorama solve the case of the Dutch Woman with Wormy Objects in Her Stool, dissect a study on cytoadhesion of...
http://www.asm.org/index.php/podcasts/twip/item/4443-what-we-know-is-confusing-twip-123
TWiP 122: If the thunder don't get you, the lightning will
Hosts: Vincent Racaniello , Dickson Despommier , and Daniel Griffin The TWiPniks docs solve the case of the Female from Peru with Epistaxis, and discuss the effect of community dewormi...
TWiP 121: A parasite without borders
Hosts: Vincent Racaniello , Dickson Despommier , and Daniel Griffin The TWiPanosome docs solve the case of the Mali Man with Profuse Diarrhea, and review the presence of Trypanosoma cr...
TWiP 120: When they die they calcify
Hosts: Vincent Racaniello , Dickson Despommier , and Daniel Griffin The TWiP triumvirate solve the case of the Thai Woman with Facial Swelling, and explain how Th17 T cells protect against ...
TWiP 119: A kinder and gentler case
Hosts: Vincent Racaniello and Daniel Griffin Vincent and Daniel solve the case of the Family with Eosinophilia, and discuss HIV-1 infection and genome integration in the blood fluke ...
TWiP 118: Crispr capers with Toxoplasma
Hosts: Vincent Racaniello , Dickson Despommier , and Daniel Griffin The TWiPinella solve the case of the Woman from Guinea, and describe the use of CRISPR/Cas9 to identify essential apicom...
TWiP 117: Parasitic puzzles
Hosts: Vincent Racaniello , Dickson Despommier , and Daniel Griffin The parasite prophets solve the case of the Thai Man with Abdominal Distention, and discuss the finding that metastat...
TWiP 116: One drug to rule them all
Hosts: Vincent Racaniello , Dickson Despommier , and Daniel Griffin The TWiPtoids solve the case of the Thai Fisherman with Chronic Diarrhea, and reveal a potential new drug for treatment ...
TWiP 115: The Cuscuta Factor
Hosts: Vincent Racaniello , Dickson Despommier , and Daniel Griffin The TWiPlets solve the sad case of the Boy Who Went Swimming, and explain why the tomato is resistant to the plant parasi...
TWiP 114: Plant potions perturb Plasmodium
Hosts: Vincent Racaniello , Dickson Despommier , and Daniel Griffin The TWiP troika solve the case of the Female from the Bronx, and reveal how feeding on different plants affects mosquit...
TWiP 113: Flying pigs
Hosts: Vincent Racaniello , Dickson Despommier , and Daniel Griffin Guest: Jason Zucker The TWiP ternion solve the case of the Man from Mexico, and discuss a transgenic toxoplasma vacc...
TWiP 112: A NOD to a tricky helminth
Hosts: Vincent Racaniello , Dickson Despommier , and Daniel Griffin The TWiP trio solve the case of the Woman from Washington Heights, and reveal how helminth infection protects mice deficie...
TWiP 111: Bug bites
Hosts: Vincent Racaniello , Dickson Despommier , and Daniel Griffin The TWiP trio solve the case of the bug bites all in a row, and talk about a secreted Toxoplasma protein that is central to...
TWiP 110: Malaria at the Bronx Zoo
Hosts: Vincent Racaniello , Dickson Despommier , and Daniel Griffin Guest: Paul Calle The TWiP trio visit the Bronx Zoo where Paul solves the case of the Four Year Old with Pulmonary Edem...
TWiP 109: Blame it on Mother
Hosts: Vincent Racaniello and Daniel Griffin Guest: Paul Daniel and Vincent solve the case of the Truck Driver from India, discuss why parasites resistant to an antimalarial drug are no...
TWiP 108: B1 cells and Leishmania, insider traitors
Hosts: Vincent Racaniello , Dickson Despommier , and Daniel Griffin The case of the Man from Assam is solved, and phagocytosis of Leishmania by B-1 cells is brought to you by the Three T...
TWiP 107: Parasites leave a bad taste in my gut
Hosts: Vincent Racaniello , Dickson Despommier , and Daniel Griffin The TWiPtastic trio solves the case of the Surfer from Switzerland, and reveal how taste-chemosensory tuft cells in t...
TWiP 106: Trematode stormtroopers in snail wars
Hosts: Vincent Racaniello , Dickson Despommier , and Daniel Griffin The TWiP triumvirate solves the case of the Missionary in Kenya, and review the finding of a soldier caste in flatworms t...
TWiP 105: Survival of the fattest
Hosts: Vincent Racaniello , Dickson Despommier , and Daniel Griffin The TWiPanosomes solve the case of the Young Man from Anchorage, and discuss how cestode parasites increase the resistance ...
TWiP 104: La maladie du sommeil
Hosts: Vincent Racaniello , Dickson Despommier , and Daniel Griffin Guest: Michael Libman Michael returns to help the TWiP trio solve the case of the Delusional African Expatriate, and dis...
TWiP 103: Scroll down, please
Hosts: Vincent Racaniello , Dickson Despommier , and Daniel Griffin Guest: Michael Libman The TWiP-scholars solve the case of the Housewife from Kolkata, discuss mutations in the IL17 gen...
TWiP 102: Nursing eosinophils
Hosts: Vincent Racaniello , Dickson Despommier , and Daniel Griffin The TWiPyzoites solve the case of the Uncommon Parasite, and discuss the role of eosinophils in promoting the growth of ...
TWiP 101: Is it round or is it flat?
Hosts: Vincent Racaniello , Dickson Despommier , and Daniel Griffin The doctors TWiP solve the case of the Woman with White Worms, and explain the role of a secreted growth factor from ...
TWiP 100: Driving past a milestone
Hosts: Vincent Racaniello , Dickson Despommier , and Daniel Griffin The TWiP trifecta solves the case of the Woman from Bolivia with Belly Pain, and discuss a method for population modifica...
TWiP 99: You get your polar bear from your nana
The TWiP trifecta solves the case of the Professor Who Went to Brazil, and discuss an amazing case of a tapeworm that turned into a tumor in an AIDS patient. Hosts: Vincent Racaniello , Dicks...
http://www.microbeworld.org/podcasts/this-week-in-parasitism/archives/2037-twip-99
TWiP 98: Resistance is not futile
The TWiP-lets reveal Balamuthia infection in the Children from Peru, and discuss resistance to pyrethroids revealed by RNA sequencing of Anopheles mosquitoes. Hosts: Vincent Racaniello , ...
http://www.microbeworld.org/podcasts/this-week-in-parasitism/archives/2017-twip-98
TWiP 97: The seven year itch
The paratenic hosts reveal a case of scabies in the Traveling Salesman, and discuss a role for natural antibody in protection from infection with Plasmodium. Hosts: Vincent Racaniello , Dick...
http://www.microbeworld.org/podcasts/this-week-in-parasitism/archives/2007-twip-97
TWiP 96: Salivary pharmacopeia
The TWiPanosomes solve the case about the Young Woman who Went to Belize, and relate how sandfly saliva skews the immune response and increases risk of cutaneous leishmaniasis. Hosts: Vincent ...
http://www.microbeworld.org/podcasts/this-week-in-parasitism/archives/2001-twip-96
TWiP 95: Arsenic and Leishmania
Vincent, Dickson, and Daniel solve the case about the 33 year old Chinese male with watery diarrhea, and discuss whether arsenic in drinking water might lead to treatment failures for Leishmania...
http://www.microbeworld.org/podcasts/this-week-in-parasitism/archives/1985-twip-95
TWiP 94: Loa hanging fruit
Vincent, Dickson, and Daniel solve the case about the man from El Salvador, discuss the use of tyrosine kinase inhibitors to treat onchocerciasis and filariasis. Hosts: Vincent Racaniello , D...
http://www.microbeworld.org/podcasts/this-week-in-parasitism/archives/1974-twip-94
TWiP 93: A fishy tale unfolds
Vincent, Dickson, and Daniel solve their fishy tale, and present a new case study for your consumption. Hosts: Vincent Racaniello , Dickson Despommier , and Daniel Griffin LINKS FOR THIS EP...
http://www.microbeworld.org/podcasts/this-week-in-parasitism/archives/1955-twip-93
TWiP 92: Kleptohaemodeipnonism
Vincent, Dickson, and Daniel discuss how fluctuation in the price of guinea pig food could help transmission of the agent of Chagas disease, and present a new case study for your consumption. H...
http://www.microbeworld.org/podcasts/this-week-in-parasitism/archives/1939-twip-92
TWiP 91: Born to deform
Vincent, Dickson, and Daniel review how Viagra might be used to block transmission of Plasmodium falciparum, and introduce a new case study. Hosts: Vincent Racaniello , Dickson Despommier ,...
http://www.microbeworld.org/podcasts/this-week-in-parasitism/archives/1929-twip-91
TWiP 90: A carbuncle is a large furuncle
Vincent, Dickson, and Daniel discuss identification of an erythrocyte protein essential for invasion of Plasmodium falciparum, and introduce a new case study. Hosts: Vincent Racaniello , Dic...
http://www.microbeworld.org/podcasts/this-week-in-parasitism/archives/1912-twip-90
TWiP 89: Day TWiPers
Vincent, Dickson, and Daniel reveal last week's case study and introduce a new one concerning a patient who traveled to Belize. Hosts: Vincent Racaniello , Dickson Despommier , and Daniel Gri...
http://www.microbeworld.org/component/content/article?id=1903
TWiP 88: French foreign lesion
Vincent, Dickson, and Daniel discuss how a secreted protein from the protozoan parasite Theileria transforms its host cells via a cellular proto-oncogene. Hosts: Vincent Racaniello , Dickso...
http://www.microbeworld.org/podcasts/this-week-in-parasitism/archives/1893-twip-88
TWiP 87: Stumped by pinworm
Vincent, Dickson, and Daniel review new insight into antigenic variation in trypanosomes, reveal the difficult solution to the last case study, and present another mystery for your solving. Hos...
http://www.microbeworld.org/component/content/article?id=1887
TWiP 86: Worms Loa the immune response to mycobacteria
Vincent, Dickson, and Daniel discuss how filarial infection modulates the immune response to mycobacterial infection, and reveal a new case study. Hosts: Vincent Racaniello , Dickson Despommi...
http://www.microbeworld.org/podcasts/this-week-in-parasitism/archives/1873-twip-86
TWiP 85: Channeling tryps
Vincent, Dickson, and Daniel explain how trypanolytic factor forms membrane channels to lyse trypanosomes, and present a new case study. Hosts: Vincent Racaniello , Dickson Despommier , and D...
http://www.microbeworld.org/podcasts/this-week-in-parasitism/archives/1864-twip-85
TWiP 84: Bigfoot
Vincent, Dickson, and Daniel consider the delivery of anti-trypanosome nanobodies to the tsetse fly via a bacterial symbiont, and present a new case study. Hosts: Vincent Racaniello , Dickson...
http://www.microbeworld.org/podcasts/this-week-in-parasitism/archives/1856-twip-84
TWiP 83: Hidden costs of infection
Vincent, Dickson, and Daniel present a new case study, and discuss the effect of chronic malaria infection on wild warbler life span and telomere degradation. Hosts: Vincent Racaniello , Dick...
http://www.microbeworld.org/podcasts/this-week-in-parasitism/archives/1852-twip-83
TWiP 82: A NOD to helminths
Vincent, Dickson, and Daniel solve last week's case study, present a new one, and reveal how secreted proteins from a helminth prevent diabetes in mice. Hosts: Vincent Racaniello , Dickson De...
http://www.microbeworld.org/podcasts/this-week-in-parasitism/archives/1844-twip-082
TWiP 81: Living in a wormy world
Vincent, Dickson, and Daniel provide the solution to last week's case study, present a new one, and discuss how immune suppression by nematodes increases tuberculosis fatality in African buffalo....
http://www.microbeworld.org/podcasts/this-week-in-parasitism/archives/1837-twip-81
TWiP 80: Daniel in the parasites' den
Vincent and Dickson welcome new TWiP host Daniel to discuss the association of a new Mycoplasma with Trichomoniasis, and to introduce a new feature to the show, a case study. Hosts: Vincent ...
http://www.microbeworld.org/podcasts/this-week-in-parasitism/archives/1829-twip-80
TWiP 79: Across the river and into the trees
Vincent and Dickson discuss the spread of P. knowlesi in Malaysia, and how Leishmania parasites protect the sandfly gut from bacterial infection. Hosts: Vincent Racaniello and Dickson D...
http://www.microbeworld.org/component/content/article?id=1806
TWiP 78: Eau de rodent
Vincent and Dickson discuss how malaria parasites induce odors in their rodent hosts that attract mosquitoes. Hosts: Vincent Racaniello and Dickson Despommier LINKS FOR THIS EPISODE: V...
http://www.microbeworld.org/podcasts/this-week-in-parasitism/archives/1792-twip-78
TWiP 77: Mixed messages
Vincent and Dickson discuss the exchange of messenger RNAs between a parasitic plant and its hosts. Hosts: Vincent Racaniello and Dickson Despommier LINKS FOR THIS EPISODE: Exchange of...
http://www.microbeworld.org/podcasts/this-week-in-parasitism/archives/1772-twip-77
TWiP 76: Herpesvirus worms its way out
Vincent and Dickson discuss how infection of mice with helminths induces cytokines that reactivate a latent gamma-herpesvirus. Hosts: Vincent Racaniello and Dickson Despommier LINKS FOR ...
http://www.microbeworld.org/component/content/article?id=1752
TWiP 75: Parasite wonders with Bobbi Pritt
Bobbi Pritt joins Vincent and Dickson to talk about directing a clinical parasitology laboratory and her weekly case reports at Creepy Dreadful Wonderful Parasites. Hosts: Vincent Racaniello �...
http://www.microbeworld.org/podcasts/this-week-in-parasitism/archives/1730-twip-75
TWiP 74: Nature has all the answers, what is your question?
Vincent and Dickson review a novel malaria vaccine candidate comprising a parasite protein involved in egress from red blood cells. Hosts: Vincent Racaniello and Dickson Despommier LINKS...
http://www.microbeworld.org/podcasts/this-week-in-parasitism/archives/1719-twip-74
TWiP 73: I'm nibbling my way back to you
Vincent and Dickson discuss how nibbling of human cells by Entamoeba histolytica, a process called amoebic trogocytosis, contributes to cell killing and tissue invasion. Hosts: Vincent Racani...
http://www.microbeworld.org/podcasts/this-week-in-parasitism/archives/1707-twip-73
TWiP 72: Wormholes
Vincent and Dickson discuss five ways that helminths manipulate host tissues to survive. Hosts: Vincent Racaniello and Dickson Despommier LINKS FOR THIS EPISODE: Wormholes in host de...
http://www.microbeworld.org/podcasts/this-week-in-parasitism/archives/1692-twip-72
TWiP 71: Happy trails to you
Hosts: Vincent Racaniello and Dickson Despommier Vincent and Dickson review the finding that urocanic acid in the skin is a chemoattractant for the parasitic nematode Strongyloides sterco...
http://www.microbeworld.org/podcasts/this-week-in-parasitism/archives/1673-twip-71
TWiP 70: Invasion of the swamp eels
Hosts: Vincent Racaniello and Dickson Despommier Vincent and Dickson discuss the finding of Gnathostoma nematodes in Asian swamp eels from US live markets and wild populations. LINKS F...
http://www.microbeworld.org/podcasts/this-week-in-parasitism/archives/1660-twip-70
TWiP 69: Malaria rising
Hosts: Vincent Racaniello and Dickson Despommier Vincent and Dickson discuss an increase in the altitude of malaria distribution in warmer years in the highlands of Colombia and Ethiopia. ...
http://www.microbeworld.org/podcasts/this-week-in-parasitism/archives/1653-twip-69
TWiP 68: Sex and the single trypanosome
Hosts: Vincent Racaniello Dickson Despommier , and Sagi Shapira Vincent, Dickson, and Sagi discuss evidence that the pathogen Trypanosoma brucei undergoes meiosis and sexual reproduction...
http://www.microbeworld.org/podcasts/this-week-in-parasitism/archives/1641-twip-68
TWiP 67: They find each other delightful
Hosts: Vincent Racaniello and Dickson Despommier Vincent and Dickson explain the genetic and molecular basis of drug resistance in Schistosoma mansonii. LINKS FOR THIS EPISODE: Basis ...
http://www.microbeworld.org/podcasts/this-week-in-parasitism/archives/1631-twip-67
TWiP 66: A nitrile warhead for Chagas disease
Hosts: Vincent Racaniello and Dickson Despommier Vincent and Dickson discuss reversible inhibitors of cruzipain as new drugs for treating Chagas disease. LINKS FOR THIS EPISODE: Revers...
http://www.microbeworld.org/podcasts/this-week-in-parasitism/archives/1623-twip-67
TWiP 65: The real world wide web
Hosts: Vincent Racaniello and Dickson Despommier Vincent and Dickson consider the effects of climate change on parasitic diseases. LINKS FOR THIS EPISODE: Climate change and infectio...
http://www.microbeworld.org/podcasts/this-week-in-parasitism/archives/1609-twip-65
TWiP 64: Three new ways to prevent malaria
Hosts: Vincent Racaniello and Dickson Despommier Vincent and Dickson review three novel approaches to antimalarial chemotherapy. LINKS FOR THIS EPISODE: Targeting PI(4)K to eliminat...
TWiP 63: Plasmodium of the apes
Hosts: Vincent Racaniello and Dickson Despommier Vincent and Dickson discuss evidence that the malaria parasite originated in gorillas. LINKS FOR THIS EPISODE: Great apes and zoonoses...
TWiP 62: More bats out of hell
Hosts: Vincent Racaniello and Dickson Despommier Vincent and Dickson discuss the high diversity of malaria parasites in West African bats, and a vaccine against hookworm. LINKS FOR THIS ...
TWiP 61: Some creep crept into the crypt and crapped
Hosts: Vincent Racaniello and Dickson Despommier Vincent and Dickson review examples of paleoparasitology, the detection of parasites in archaeological material. LINKS FOR THIS EPISODE: ...
http://www.microbeworld.org/podcasts/this-week-in-parasitism/archives/1492-twip-61
TWiP 60: Urine a game of cat and mouse
Hosts: Vincent Racaniello and Dickson Despommier Vincent and Dickson discuss how infection with Toxoplasma gondii causes mice to lose their aversion to cat urine, even after the parasite...
http://www.microbeworld.org/component/content/article?id=1478
TWiP 59: Apicomplexity
Hosts: Vincent Racaniello and Dickson Despommier Vincent and Dickson update the multistate outbreak of cyclosporiasis, discuss the avian malaria parasite P. lophurae, and review protectio...
http://www.microbeworld.org/podcasts/this-week-in-parasitism/archives/1467-twip-59-apicomplexity
TWiP 58: People, parasites, and plowshares
Hosts: Vincent Racaniello and Dickson Despommier Guest: Cali Despommier Vincent and Dickson update the multistate outbreak of cyclosporiasis, and Dickson reads a chapter from his new boo...
TWiP 57: An outbreak of cyclosporiasis
Hosts: Vincent Racaniello and Dickson Despommier Vincent and Dickson review a multistate outbreak of cyclosporiasis caused by the single-celled coccidian parasite Cyclospora cayetanensis...
http://twip.libsyn.com/t-wi-p-57-an-outbreak-of-cyclosporiasis
TWiP 56: Whirling disease
Hosts: Vincent Racaniello and Dickson Despommier Vincent and Dickson discuss Myxobolus cerebralis, the parasite that causes whirling disease of salmonids. Links for this episode: Myxobo...
http://www.microbeworld.org/podcasts/this-week-in-parasitism/archives/1425-twip-56-whirling-disease
TWiP 55: A ladybird's weapon
Hosts: Vincent Racaniello and Dickson Despommier Vincent and Dickson reveal how invasive harlequin ladybirds use biological weapons against their competitors. LINKS FOR THIS EPISODE: I...
TWiP 54: Unde venis?
Hosts: Vincent Racaniello and Dickson Despommier Vincent and Dickson consider a case history of a young man with Blastocystis hominis - is it causing his disease? LINKS FOR THIS EPISOD...
http://www.microbeworld.org/podcasts/this-week-in-parasitism/archives/1400-twip-54-unde-venis
TWiP 53: Anti-saliva immunity
Hosts: Vincent Racaniello and Dickson Despommier Vincent and Dickson discuss the finding that immunity to a sandfly salivary protein protects against fatal visceral leishmaniasis in hamste...
http://www.microbeworld.org/component/content/article?id=1386
TWiP 52: Not your ordinary unsegmented roundworm
Hosts: Vincent Racaniello and Dickson Despommier Vincent and Dickson review the life cycle and pathogenesis of the giant kidney worm, Dioctophyme renale. LINKS FOR THIS EPISODE: Dioct...
TWiP 51: Modifying mosquitoes with Anthony A. James
Hosts: Vincent Racaniello and Dickson Despommier Guest: Anthony A. James Special guest Anthony A. James joins Vincent and Dickson to discuss how mosquitoes can be genetically modified ...
TWiP 50: Antagonism in the mosquito midgut
Hosts: Vincent Racaniello and Dickson Despommier Vincent and Dickson reveal how malaria parasites avoid lysis by complement in the mosquito. LINKS FOR THIS EPISODE: Malaria parasites ...
TWiP 49: Making sense of toxo and heme
Hosts: Vincent Racaniello and Dickson Despommier Vincent and Dickson discuss innate immune sensing of Toxoplasma gondii in mice, and heme metabolism in protozoan parasites. LINKS FOR T...
TWiP 48: A parasitic cloaking device
Hosts: Vincent Racaniello , Dickson Despommier , and Josef Sabo Vincent, Dickson, and Josef discuss tetraspanins on the surface of schistosomes as vaccine candidates and immune evasion protei...
TWiP 47: For whom the trich tolls
Hosts: Vincent Racaniello and Dickson Despommier Vincent and Dickson review evidence that a virus of the protozoan parasite Trichomonas vaginalis may exacerbate disease. LINKS FOR THIS...
TWiP 46: Malaria gets the (zinc) finger
Hosts: Vincent Racaniello and Dickson Despommier Vincent and Dickson meet with Judith Straimer and Marcus Lee to discuss their method for site-specific genome editing in Plasmodium falcip...
TWiP 45: Free range Toxoplasma with John Boothroyd
Hosts: Vincent Racaniello and Dickson Despommier Vincent and Dickson discuss Toxoplasma biology with Stanford University Professor John Boothroyd . LINKS FOR THIS EPISODE: T. gondii...
TWiP 44: Parasites provide a cricket subsidy for trout
Hosts: Vincent Racaniello and Dickson Despommier Vincent and Dickson explain how a nematode manipulates cricket behavior and alters the food web of a stream. LINKS FOR THIS EPISODE: Ne...
TWiP 43: Two remarkable host-parasite conflicts
Vincent and Dickson review how sickle cell microRNAs contribute to malaria resistance, and inhibition of innate immune responses by an enzyme from trypanosomes. LINKS FOR THIS EPISODE: microR...
TWiP 42: The tick keeps on ticking
Hosts: Vincent Racaniello and Dickson Despommier Vincent and Dickson answer listener emails about Leishmania, dual infection of vectors, tapeworms, liver flukes, toxoplasmosis, and much m...
TWiP 41: Flying and crawling beasts
Hosts: Vincent Racaniello and Dickson Despommier Vincent and Dickson review medically important arthropods. LINKS FOR THIS EPISODE: Thomas Eisner Incomplete metamorphosis in insects...
TWiP 40: Doctor, there's a worm in my eye!
Hosts: Vincent Racaniello and Dickson Despommier Vincent and Dickson discuss loaiasis caused by the filarial nematode Loa loa. Right-click to download TWiP #40 (52 MB .mp3, 73 minute...
TWiP 39: I encyst, said the amoeba
Hosts: Vincent Racaniello and Dickson Despommier Vincent and Dickson review the biology and pathogenesis of the amoebae Naegleria fowlerii and Acanthamoeba castellani. LINKS FOR THIS ...
TWiP 38: How to Trichomonas
Hosts: Vincent Racaniello and Dickson Despommier Vincent and Dickson tackle the backlog of listener email, then consider the life cycle and pathogenesis of Trichomonas vaginalis, the fla...
TWiP 37: Dracunculiasis
Vincent and Dickson discuss the life cycle and pathogenesis of Dracunculus medinensis, the filarial nematode that causes dracunculiasis, or Guinea worm disease. LINKS FOR THIS EPISODE: Dracun...
TWiP 36: Trichuris and microbes plan a hatch
Vincent and Dickson review how gut bacteria help establish T. muris in the large intestine of mice.
TWiP 35: Malaria control with David Fidock
Vincent and Dickson discuss control of malaria with their Columbia University colleague David Fidock .
TWiP #34 - Up against the Wolbachia
Vincent and Dickson discuss control of malaria and filariasis with the bacterial endosymbiont Wolbachia.
TWiP #33 - Hide and seek
Vincent and Dickson review an in silico pipeline for identifying molecular mimicry candidate proteins in the genomes of parasites, and catch up on listener email.
TWiP #32: Evasive trypanosomes and schistosomes
Vincent and Dickson discuss immune evasion by the cruzain protease of T. cruzi, and novel tetraspanin antigens of S. japonicum.
TWiP #31 - A malaria vaccine
Vincent and Dickson discuss the promising results of a phase III trial of a malaria vaccine in African children.
http://www.virology.ws/2011/10/20/twip-31-a-malaria-vaccine/
TWiP #30 - Global infectious disease control with Charles Knirsch
Vincent and Dickson have a broad-ranging conversation with Charles Knirsch of Pfizer, Inc. about how public-private partnerships can function to control and eliminate infectious diseases.
TWiP #29 - Neglected tropical diseases with Peter Hotez
Vincent and Dickson converse with Peter Hotez about global health, vaccinology, and neglected tropical diseases.
TWiP #28 - Medical entomology with Robert W. Gwadz
Vincent and Dickson discuss medical entomology with Robert W. Gwadz, Assistant Chief of the Laboratory of Malaria and Vector Research at NIAID.
TWiP #27 - Trematodes
Vincent and Dickson continue their discussion of trematodes, or flukes, which have a snail as a reservoir host.
TWiP #26 - The schistosomes
Vincent and Dickson take on the schistosomes, agents of a series of related diseases in humans referred to as schistosomiasis.
TWiP #25 - Wuchereria bancrofti
Vincent and Dickson review Wuchereria bancrofti, the nematode that causes lymphatic filariasis, also known as elephantiasis.
TWiP #24 - Onchocerca volvulus, a vector-borne, filarial nematode
Vincent and Dickson discuss the life cycle and pathogenesis of Onchocerca volvulus, the vector-borne filarial nematode parasite that causes onchocerciasis, or river blindness.
http://www.microbeworld.org/index.php?option=com_content&view=article&id=904
TWiP #23 - Strongyloides sterocoralis, a most unusual parasite
Vincent and Dickson review the life cycle and pathogenesis of the world's most unusual parasite, Strongyloides stercoralis.
TWiP 22 - Hookworm
Vincent and Dickson discuss possibly the most socially and politically important nematode of humans, the hookworm Ancylostoma duodenale and Necator americanus.
TWiP #21 - The giant intestinal worm, Ascaris lumbricoides
Vincent and Dickson review the biology and pathogenesis of Ascaris lumbricoides, one of the largest nematodes to infect humans.
TWiP #20 - The whipworm Trichuris trichiura
Vincent and Dickson continue their discussion of nematodes with the whipworm Trichuris trichiura. Host links: Vincent Racaniello and Dickson Despommier LINKS FOR THIS EPISODE: Trichuris ...
TWiP #19 - Enterobius vermicularis, the pinworm
Vincent and Dickson move on to nematodes with a discussion of the pinworm Enterobius vermicularis. Host links: Vincent Racaniello and Dickson Despommier LINKS FOR THIS EPISODE: Enterobius...
http://www.microbeworld.org/index.php?option=com_content&view=article&id=813
TWiP #18 - Cryptosporidium
Vincent and Dickson discuss the intracellular parasite Cryptosporidium, which causes diarrheal disease in most mammalian species. Host links: Vincent Racaniello and Dickson Despommier LINKS...
http://www.microbeworld.org/index.php?option=com_content&view=article&id=800
TWiP #17 - Entamoeba histolytica
Vincent and Dickson continue their discussion of protozoan parasites that cause diarrhea with a review of amebic dysentery caused by Entamoeba histolytica. Host links: Vincent Racaniello and D...
http://www.microbeworld.org/index.php?option=com_content&view=article&id=782
TWiP #16: Giardia
Vincent and Dickson review the life cycle and pathogenesis of the flagellated protozoan parasite Giardia lamblia. Host links: Vincent Racaniello and Dickson Despommier LINKS FOR THIS EPISOD...
http://www.microbeworld.org/index.php?option=com_content&view=article&id=770
TWiP #15: Tryp the light fantastic
Vincent and Dickson discuss the life cycle and pathogenesis of the protozoan parasite Trypanosoma. Host links: Vincent Racaniello and Dickson Despommier LINKS FOR THIS EPISODE: Metacyclic...
TWiP #14 - Leishmania
Vincent and Dickson consider the life cycle and pathogenesis of the protozoan parasite Leishmania. Host links: Vincent Racaniello and Dickson Despommier LINKS FOR THIS EPISODE: L. bra...
http://feedproxy.google.com/~r/parasitism/~3/-O32wMw77D4/twip014
TWiP #13 - Toxoplasmosis
Vincent and Dickson continue their discussion of the obligate intracellular protozoan Toxoplasma gondii with a consideration of the clinical consequences of infection and pathogenesis. Host lin...
http://feedproxy.google.com/~r/parasitism/~3/sPLiYVsYz1o/twip013
TWiP #12 - Toxoplasma gondii
Vincent and Dickson introduce the obligate intracellular protozoan Toxoplasma gondii, one of the most successful parasites on earth. Host links: Vincent Racaniello and Dickson Despommier LI...
http://feedproxy.google.com/~r/parasitism/~3/1CqnsnnRZ6Y/twip012
TWiP #11 - One times three million
Vincent and Dickson continue their discussion of malaria, with emphasis on clinical aspects of the disease. Host links: Vincent Racaniello and Dickson Despommier LINKS FOR THIS EPISODE: ...
http://feedproxy.google.com/~r/parasitism/~3/c7KKlZ2caGY/twip011
TWiP #10 - Plasmodium life cycle
Vincent and Dickson trace the life cycle of Plasmodium in a mosquito and in a human host. Host links: Vincent Racaniello and Dickson Despommier LINKS FOR THIS EPISODE: Mosquito cycle - s...
http://feedproxy.google.com/~r/parasitism/~3/QazRC3GZ-Gw/twip010
TWiP #9 - Mala aria
Vincent and Dickson move on to protozoan parasites with a discussion of the early history of malaria. Host links: Vincent Racaniello and Dickson Despommier LINKS FOR THIS EPISODE: Malaria...
http://feedproxy.google.com/~r/parasitism/~3/Zfu3hp-fByI/twip009
TWiP #8 - Frog legs and parasite tales
Dickson reads his story about sparganosis caused by the diphyllobothroid tapeworm Spirometra mansonoides. Host links: Vincent Racaniello and Dickson Despommier LINKS FOR THIS EPISODE: ...
http://feedproxy.google.com/~r/parasitism/~3/bPT93dboZX8/ah3u3q
TWiP #7 - Tapeworms are fantastic!
Vincent and Dickson continue their discourse on tapeworms, covering the fish and dog varieties. Host links: Vincent Racaniello and Dickson Despommier LINKS FOR THIS EPISODE: FAT the enemy...
http://feedproxy.google.com/~r/parasitism/~3/gu0E64sy0W8/cyhhdF
TWiP #6 - Tapeworms, the long and short of it
Vincent and Dick talk about the anatomy and life cycle of beef and pork tapeworms, and why House was wrong about neurocysticercosis. Host links: Vincent Racaniello and Dickson Despommier L...
http://feedproxy.google.com/~r/parasitism/~3/cMaGkJ2NXUM/924Cen
TWiP #5 - The nurse cell
Vincent and Dick discuss the nurse cell, a unique structure formed in the host muscle by Trichinella species. Host links: Vincent Racaniello and Dickson Despommier LINKS FOR THIS EPISODE: ...
http://feedproxy.google.com/~r/parasitism/~3/s0CzUeYhJuA/9xJTPb
TWiP #4 - Trichinella life cycle
Vincent and Dick trace the life cycle of Trichinella spiralis in an infected host. Host links: Vincent Racaniello and Dickson Despommier LINKS FOR THIS EPISODE: Trichinella life cycle (j...
http://feedproxy.google.com/~r/parasitism/~3/Cf_mdalcneg/cQGGAP
TWiP #3 - Trichinella spiralis
Vincent and Dick distinguish among intracellular and extracellular parasites, then discuss the history and general characteristics of Trichinella spiralis. Host links: Vincent Racaniello and...
http://feedproxy.google.com/~r/parasitism/~3/rXOBzcDxHIU/5kW1zf
TWiP #2 - General parasitism
Vincent and Dick classify parasites according to whether or not they are transmitted by a vector, then consider the implications of long-lived parasites. Host links: Vincent Racaniello and D...
http://feedproxy.google.com/~r/parasitism/~3/g6_8cVph3EE/6Ct2hq
TWiP #1 - Introduction to parasitism
Vincent and Dick provide an overview of parasites and parasitism. Host links: Vincent Racaniello and Dickson Despommier WEEKLY SCIENCE PICKS Dick T he Black Cloud by Fred Hoyle Vincent P...
http://feedproxy.google.com/~r/parasitism/~3/rMNVArIm8X0/2O6NRb