Asian Scientist Magazine | Science, Technology and Medicine News Updates From Asia » Gene Editing

By replacing insecticide-resistant genes in fruit flies with susceptible forms, an India-US research team is devising ways to lower insecticide use in farms.

https://www.asianscientist.com/2022/02/in-the-lab/genetic-engineering-insecticide-resistance/

Scientists are fighting drug-resistant microbes with a new CRISPR-Cas gene editing method that can be transferred between bacterial strains.

https://www.asianscientist.com/2021/09/in-the-lab/crispr-multidrug-resistant-pathogens/

Researchers from Singapore have developed a CRISPR/Cas9-base gene editor capable of correcting single-letter mutations in our DNA sequence.

https://www.asianscientist.com/2021/06/in-the-lab/crispr-ctog-base-editor/

CRISPR has come a long way since it burst into the public imagination in the last decade. Here’s a glimpse of the top trends in gene editing for 2020 and beyond.

https://www.asianscientist.com/2020/10/print/crispr-crystal-ball/

When Yoshizumi Ishino first encountered in 1986 the mysterious sequences that would later come to be known as CRISPR, he was as far away from the present day as he was to the discovery of the dou...

https://www.asianscientist.com/2020/10/print/crispr-discovery-yoshizumi-ishino/

It’s been nearly a decade since CRISPR captured public imagination. As the technology matures, we’ve rounded up some of CRISPR’s most interesting use cases to emerge in recent years.

https://www.asianscientist.com/2020/10/print/crispr-takes-center-stage/

Researchers have modified the Cas9 enzyme to create a version that is 93 times more accurate than what is found in nature.

https://www.asianscientist.com/2020/08/in-the-lab/cas9-mutation-crispr-accuracy/

Scientists have used gene editing to create mice expressing human ACE2, the receptor used by SARS-CoV-2 to enter cells.

https://www.asianscientist.com/2020/06/in-the-lab/crispr-mouse-model-covid-19/

For gene editing technologies like CRISPR to make a positive impact on agriculture, they must be embraced by companies both big and small. Corteva Agriscience is encouraging open innovation to he...

https://www.asianscientist.com/2020/05/features/corteva-crispr-cas9-food-crops-mathias-muller/

Prime editing, a new genome editing approach, has great potential for plant breeding and functional genomic research.

https://www.asianscientist.com/2020/04/in-the-lab/prime-editing-rice-wheat/

Corals are dying but science could be able to help them fight back from the brink.

https://www.asianscientist.com/2019/12/features/aswp2019-corals-turn-of-the-tide/

They may not be as charismatic as the pandas or polar bears, but insects are indispensable to life as we know it.

https://www.asianscientist.com/2019/12/features/aswp2019-insect-apocalypse/

Researchers in Japan have devised a tool to edit plant mitochondrial DNA and develop new strains of crop plants.

https://www.asianscientist.com/2019/07/in-the-lab/plant-mitochondrial-dna-editing-mitotalens/

A China-led research collaboration has resulted in a technique to identify single nucleotide variations, insertions and deletions potentially introduced by gene editors like CRISPR-Cas9.

https://www.asianscientist.com/2019/03/in-the-lab/embryo-gene-editing-crispr-goti/

Prominent personalities, therapies for HIV infection and cool feats of engineering were topics of interest in the month of May.

https://www.asianscientist.com/2018/06/topnews/7-must-read-stories-may-2018/

Scientists have discovered a specific gene mutation that reduces the buildup of amyloid-beta plaques in a mouse model of Alzheimer’s disease.

https://www.asianscientist.com/2018/05/in-the-lab/alzheimers-amyloid-precursor-protein-mutation/

Researchers have used gene editing to block the replication of HIV in human cells.

https://www.asianscientist.com/2018/05/in-the-lab/crispr-cas9-gene-editing-hiv/

A gene regulating the fight-or-flight response is more active in humans and chimpanzees than more peaceful primates, researchers say.

https://www.asianscientist.com/2018/04/in-the-lab/humans-chimps-fight-flight-response/

Using gene editing to systematically screen a large number of tumor suppressor genes, researchers in China have identified five genes linked to lung tumor growth.

https://www.asianscientist.com/2018/04/in-the-lab/lung-cancer-crispr-in-vivo-screen/

Using the CRISPR/Cas9 gene editing system, researchers have developed a pig model of Huntington’s disease that better mimics how the disease progresses in humans.

https://www.asianscientist.com/2018/04/in-the-lab/crispr-pig-model-huntingtons-disease/

February saw the successful cloning of monkeys, intercontinental quantum communication and the fast tracking of a Zika vaccine candidate.

https://www.asianscientist.com/2018/03/topnews/7-must-read-stories-february-2018/

By using a phosphatase to remove a chemical group on synthetic guide RNAs, scientists in South Korea have made CRISPR-Cas9 less immunogenic and less toxic.

https://www.asianscientist.com/2018/03/in-the-lab/crispr-innate-immune-activation/

Scientists at Osaka University in Japan have developed a modified Cas9 enzyme that greatly suppresses the rate of unintended genetic mutation compared to conventional methods.

https://www.asianscientist.com/2018/02/in-the-lab/crispr-cas9-nick-precision/

Merck’s patent covers the successful integration of an external DNA sequence into the chromosome of eukaryotic cells using CRISPR gene editing.

https://www.asianscientist.com/2017/12/pharma/merck-singapore-crispr-patent/

Using high-speed atomic-force microscopy, scientists in Japan have observed how the CRISPR/Cas9 complex cuts DNA in real-time.

https://www.asianscientist.com/2017/11/in-the-lab/crispr-cas9-afm-video/

Researchers in Hong Kong and France have genetically engineered tomatoes with enhanced antioxidant properties.

https://www.asianscientist.com/2017/11/in-the-lab/gene-engineering-antioxidant-tomato/

Scientists in Hong Kong have developed a method to carry the CRISPR/Cas9 gene editing system into bone tumors, thus enabling therapeutic gene editing.

https://www.asianscientist.com/2017/11/in-the-lab/aptamer-delivery-crispr-osteosarcoma/

Using CRISPR/Cas gene-editing, scientists in China have introduced a gene into pigs that makes them lean and cold-resistant.

https://www.asianscientist.com/2017/10/in-the-lab/crispr-pig-fat-deposition/

The ability to change the color of the Japanese morning glory demonstrates the specificity of the CRISPR-Cas9 gene editing system.

https://www.asianscientist.com/2017/09/in-the-lab/morning-glory-color-violet/

A monkey model of autism could help researchers better understand the disease in humans.

https://www.asianscientist.com/2017/08/in-the-lab/monkey-autism-genes-brain/