c-Jun N-terminal kinase (JNK) contributes to the pathogenesis of diabetic nephropathy (DN). The JNK inhibitor SP600125 was reported to ameliorate DN. However, the mechanism remained unclear. We p...
http://jme.endocrinology-journals.org/cgi/content/short/60/2/145?rss=1
Androgens act in concert with vitamin D to influence reabsorption of calcium. However, it is unclear whether androgens directly regulate vitamin D homeostasis or control other cellular events tha...
http://jme.endocrinology-journals.org/cgi/content/short/60/2/159?rss=1
Our earlier studies have demonstrated the cyclic variation and also the altered expression of sorcin in endometrium during early-to-mid-secretory phase transition in women with unexplained infert...
http://jme.endocrinology-journals.org/cgi/content/short/60/2/119?rss=1
Preeclampsia (PE) is a pregnancy-induced disorder characterized by hypertension and proteinuria after 20 weeks of gestation, affecting 5–7% of pregnancies worldwide. So far, the etiology of PE ...
http://jme.endocrinology-journals.org/cgi/content/short/60/2/133?rss=1
Unbiased genomic screening analyses have highlighted novel immunomodulatory properties of the active form of vitamin D, 1,25-dihydroxyvitamin D (1,25(OH)2D). However, clearer interpretation of th...
http://jme.endocrinology-journals.org/cgi/content/short/60/2/95?rss=1
High-fat diet (HFD)-induced metabolic inflammation in the central and peripheral organs contributes to the pathogenesis of obesity. Long-term HFD blunts signaling by ghrelin, a gastric-derived or...
http://jme.endocrinology-journals.org/cgi/content/short/60/2/109?rss=1
Corticosteroid-binding globulin (CBG) is a plasma carrier of glucocorticoids. Human and rat CBGs have six N-glycosylation sites. Glycosylation of human CBG influences its steroid-binding activity...
http://jme.endocrinology-journals.org/cgi/content/short/60/2/71?rss=1
The situation following anti-obesity drug termination is rarely investigated, eventhough a decrease in body weight needs to be sustained. Therefore, this study examined the impact of twice-daily ...
http://jme.endocrinology-journals.org/cgi/content/short/60/2/85?rss=1
Islet amyloid polypeptide (IAPP), the main component of islet amyloid in type 2 diabetes and islet transplants, is now recognized as a contributor to beta cell dysfunction. Increasingly, evidence...
http://jme.endocrinology-journals.org/cgi/content/short/60/2/R57?rss=1
Glucocorticoid production is gated at the molecular level by the circadian clock in the adrenal gland. Stress influences daily rhythms in behavior and physiology, but it remains unclear how stres...
http://jme.endocrinology-journals.org/cgi/content/short/60/2/55?rss=1
Rupture of fetal membranes (ROM) can initiate parturition at both term and preterm. Collagen III in the compact layer of the amnion contributes to the tensile strength of fetal membranes. However...
http://jme.endocrinology-journals.org/cgi/content/short/60/2/45?rss=1
The global rise in metabolic diseases can be attributed to a complex interplay between biology, behavior and environmental factors. This article reviews the current literature concerning DNA meth...
http://jme.endocrinology-journals.org/cgi/content/short/60/2/R39?rss=1
Uroguanylin (UGN) is a potential target in the fight against obesity. The mature protein is released after enzymatic cleavage from its natural precursor, proUGN. UGN is mostly produced in the gut...
http://jme.endocrinology-journals.org/cgi/content/short/60/2/R31?rss=1