EpgntxEinstein

A tweet by cousin Hank  in the last few days brought this correspondence in Nature Biotechnology  to my attention. Entitled CHALLENGES AND RECOMMENDATIONS FOR EPIGENOMICS IN PRECISION HEALTH, ...

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Basically, there are three definitions of epigenetics plaguing the earth. The big one is the BIOCHEMISTS’ definition: epi- (above, upon) -genetic (DNA sequence). Pioneered by outstanding scie...

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If you are a journal editor, or a reviewer of a manuscript or a grant proposal, the following serves as a scoring system (maximum 10 points) for an epigenome-wide association study (EWAS), based ...

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It is always interesting to challenge people to define what they mean by epigenetics. Like obscenity, people know it when they see it, but have difficulty explaining it. When you get away from ...

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If you’re fascinated by epigenetics, as I have been my entire academic career, you may be dismayed to see the recent stream of negativity about our field, to which I have been a prolific contri...

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A few historical notes: Conrad (Hal) Waddington did not invent the word epigenetics, it was around since Aristotle over 2 millenia previously. Waddington defined the epigenetic landscape. Contr...

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If the study of epigenetic dysregulation in human diseases was a technology startup company, we’d have a problem.  Our angel investor confidence would have be shaken by the blowback about th...

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Our new #DataViz #D3js software #Pcaso http://pcaso.io/mundo Explore your own data in multiple dimensions, upload to http://pcaso.io/ @genomenathan @robaboukhalil @nygenome @einsteinmed

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UPDATE: take a look at the response of the lead author at his site , kudos to him for engaging in this constructive discussion. Epigenetics studies of interesting questions sometimes get great ...

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This weekend Twitter is buzzing about an article in The Guardian: Study of Holocaust survivors finds trauma passed on to children’s genes http://gu.com/p/4byz9/stw The gist of the Guardian...

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We need your help explaining something. Why are you still using a 121 year old technique? Blum F. 1894 Notiz über die Anwendung des Formaldehyds (Formol) als Hartungs- und Konservierungsmittel...

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The British Journal of Psychiatry has, laudably, retracted a paper on the request of co-authors who found one of the group to have fabricated DNA methylation data. There’s a lot of scandal a...

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In a Nature Comment piece a few weeks ago, an interesting perspective was raised about recent discussions of heritable, non-genetic risk for disease, making the point that this often involves di...

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I was sorry to see the news today that Jerzy Jurka has passed away. For everyone who has ever used RepeatMasker, or studied transposable elements in any way, Jerzy impacted your career. He was...

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We really need to change how we publish in the field of genomics research. Everyone knows that, but it’s one of those problems that is simultaneously daunting and nobody’s clear responsibilit...

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scientificillustration : > C. H. Waddington’s >  developmental > landscape (top) and its underpinnings (bottom) >   >  > “The ‘developmental landscape’ is a represen...

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It has been a frustrating weekend, but not for scientific reasons . Maybe that’s the motivation behind this jaundiced posting.  The epigenome-wide association study (EWAS) is a tricky beast,...

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In October there was a scientific symposium marking the opening of the New York Genome Center (NYGC). A featured event was a discussion between Bob Darnell, president of the NYGC, and Jim Watson....

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A community project on Twitter – what 25 papers would you give to a new graduate student to inform them about epigenomics? 1. My own suggestion, to kick things off, the first human methylome...

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The @EpgntxEinstein weekly review of new publications in #epigenetics via Storify http://sfy.co/aMab

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