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The Impact Of Peer Interventions On Physical Activity For Individuals Living With Mental Illness
Individuals living with mental illness have significantly reduced physical health compared to the general population, leading to a significantly decreased life expectancy. Physical activity has b...
Engineering And Evaluating Biodegradable Bioadhesive Nanoparticle-Encapsulated Sunscreens
One in five Americans are estimated to develop skin cancer during their lifetime, rendering it the most common malignancy diagnosed in the United States with associated healthcare costs estimated...
Lipid Profiles Help Explain Protection From Atherosclerosis In Ascending Aortic Aneurysm Patients
Multiple indicators including low coronary artery calcium score, low carotid intimal media thickness, and low rates of myocardial infarction have previously suggested that ascending thoracic aort...
Soil-Transmitted Helminthiases And Deworming Response In School-Aged Children In Retalhuleu, Guatemala
Background: Soil-transmitted helminthiases (STH) are amongst the most common diseases of poverty worldwide despite mass deworming campaigns. However, widespread use of benzimidazole anthelminthic...
Improving Cancer Classification With Domain Adaptation Techniques
Background: As the quantity and complexity of oncological data continue to increase, machine learning (ML) has become an important tool in helping clinicians better understand malignancies and pr...
Recording Multiunit Activity Of The Locus Coeruleus In An Awake Mouse Model Of Focal Limbic Seizures
Patients with temporal lobe seizures can suffer debilitating loss of consciousness during ictal episodes. Rat models have previously implicated the inhibition of brainstem and basal forebrain cho...
Analysis Of Prices And Outcomes For Common Hospitalized Conditions In 2021
Our study seeks to use newly disclosed hospital price transparency data to understand associations between average payer-negotiated prices, outcomes and hospital characteristics. Data on prices, ...
"Come On. I Need An Answer." A Mixed-Methods Study Of Barriers And Disparities In Diagnostic Odysseys
Background: The boom of next generation DNA sequencing over the past decade has improved our ability to provide accurate genetic diagnoses for children with previously undiagnosed diseases, in tu...
Barriers To Identifying Learning Disabilities: A Qualitative Study Of Clinicians And Educators
The estimated prevalence of learning disabilities (LDs) is nearly 8% of all children. Yet fewer than 5% of all children are diagnosed in public schools — jeopardizing remediation. The specific ...
A Novel Smarcc1-Mutant Bafopathy Implicates Epigenetic Dysr...al Progenitors In The Pathogenesis Of Congenital Hydrocephalus
Congenital hydrocephalus (CH) is a common disorder requiring neurosurgery in children, however its pathogenesis is poorly understood. Recent studies have implicated SMARCC1 as a candidate CH gene...
Baseline Skin Cytokine Profiles Determined By Rna In Situ H...h Response To Dupilumab In Patients With Eczematous Dermatitis
Dupilumab, a monoclonal antibody that inhibits IL4 and IL13, has revolutionized the treatment of atopic dermatitis (AD). However, not all patients respond optimally, and this may relate to underl...
Single-Cell Transcriptomic Atlas Reveals Molecular Drivers Of Human Inner Ear Development
Introduction: Improving the therapeutic landscape for hearing loss necessitates an improved understanding of inner ear biology. Historically, our molecular understanding of inner ear physiology h...
A Single Nucleotide Polymorphism In An Rgs6 Enhancer Regulates Heart Rate Variability And Parasympathetic Modulation
The sinoatrial node (SAN) consists of specialized pacemaker cardiomyocytes (PCs) that collectively function as the leading pacemaker of the heart. PCs have a distinct gene expression program that...
“I Was Reaching Out For Help And They Did Not Help Me”: Mental Healthcare In The Carceral State
Background: Despite the limitations the carceral environment may impose on mental wellness, mental healthcare is increasingly becoming a carceral endeavor. Over the course of the last several dec...
Utility Of Shear Wave Elastography In Breast Cancer Diagnosis: A Systematic Review And Meta-Analysis
In the United States, breast cancer is one of the most diagnosed cancers in women. Early detection, often via mammography, and intervention have been shown to reduce mortality. However, not all c...
Diagnosis Of Polycystic Ovary Syndrome And Non-Hispanic Bla...e Women -Analysis Of Real World Electronic Medical Record Data
Objective: The primary objective was to examine if blood pressure (BP) indices are higher and if the prevalence of hypertension (HTN), indices of metabolic syndrome (MetS) and severe obesity are ...
Applying Deep Learning To Identify Imaging Biomarkers To Predict Cardiac Outcomes In Cancer Patients
Cancer patients are a unique population with increased mortality from cardiovascular disease, however only half of high-risk patients are medically optimized. Physicians ascertain cardiovascular ...
Investigating Effects Of Glycolysis Inhibition On Metabolis... Extracellular Ph In A Mouse Model Of Hepatocellular Carcinoma
In this study, we investigated the effects of systemic glycolysis inhibition with 2-deoxy-D-glucose (2-DG), a glucose analogue that inhibits hexokinase, in the Hepa1-6 orthotopic mouse model of h...
Multi-Omic Differences Between Right And Left Sided Colorectal Cancer Liver Metastases
Colorectal cancer (CRC) is the second leading cause of cancer-related death both in the United States and worldwide, making it an urgent area of investigation for the oncology community. The infe...
Severity And Operative Age In Metopic Synostosis: The Association With Neurocognitive Outcomes
The cranial morphology of single-suture metopic craniosynostosis is defined by trigonocephaly, hypotelorism, and bitemporal narrowing. The severity of deformity may be defined radiographically ba...