An extensive introduction to keto-enol tautomerism in aldehydes and ketones, with mechanisms, quizzes, key concepts, references and more.
https://www.masterorganicchemistry.com/2022/06/21/keto-enol-tautomerism-key-points/
Alkene Stability (And Instability) What factors affect alkene stability? If you’ve studied elimination reactions, no doubt you’ve learned about Zaitsev’s Rule – about how elimination
https://www.masterorganicchemistry.com/2020/04/30/alkene-stability/
E and Z Notation For Alkenes Unlike C–C single bonds, C–C double bonds can’t undergo rotation without breaking the pi bond One consequence of this
https://www.masterorganicchemistry.com/2016/11/03/alkene-nomenclature-cis-and-trans-and-e-and-z/
Alkylation of acetylides Terminal alkynes have unusually acidic C–H bonds (pKa 25). Treatment with a strong base such as sodium amide (NaNH2) gives an acetylide,
http://cdn.masterorganicchemistry.com/2013/05/01/acetylide-formation-alkylation/
Alkene Addition Reactions: Regioselectivity and Stereoselectivity Almost all reactions of alkenes we will learn about can be classified as addition reactions In an alkene addition
https://www.masterorganicchemistry.com/2013/01/22/alkene-addition-regioselectivity-syn-anti/
Sometimes The “Formal Charge” Does Not Accurately Represent The Electron Density Around An Atom! Formal charges have their plusses and minuses. Har har. In many
https://www.masterorganicchemistry.com/2012/02/22/common-mistakes-formal-charges-can-mislead/
There’s a hidden layer of detail beneath chemical structures that students new to organic chemistry often miss. I’m talking about partial charges. Although each of
https://www.masterorganicchemistry.com/2011/07/11/partial-charges/
When figuring out what the product of a reaction is, there are really two important steps. 1. Figuring out where the electrons go. 2. Drawing
https://www.masterorganicchemistry.com/2011/05/31/draw-the-ugly-version-first/
Nucleophilic Acyl Substitution (With Negatively Charged Nucleophiles) Yes, there are a lot of reactions of carboxylic acid derivatives to learn! In this article we’ll explore
https://www.masterorganicchemistry.com/2011/05/06/nucleophilic-acyl-substitution/
The Second-Most Important Mechanism In Carbonyl Chemistry – Carbonyl Elimination The reverse of nucleophilic addition to the C=O bond (giving a tetrahedral intermediate) is elimination
https://www.masterorganicchemistry.com/2010/05/21/carbonyl-elimination-mechanism/